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NCT03946189 Clinical Trial

Comparison of the PaO2/FiO2 Ratio to Other Oxygenation Indexes for the Classification of Severity of Acute Respiratory Distress Syndrome

Acute Respiratory Distress Syndrome Clinical Trial

Official title:
Comparison of the PaO2/FiO2 Ratio to Other Oxygenation Indexes for the Classification of Severity of Acute Respiratory Distress Syndrome

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03946189
Other study ID # BIO-2018-0033
Secondary ID
Status Completed
Phase
First received
Last updated
Start date March 14, 2018
Est. completion date May 1, 2019

Study information
Verified date May 2019
Source American University of Beirut Medical Center
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

In mechanically ventilated patients the PaO2/FiO2 ratio might not be the best reflection of the severity of ARDS. It does not incorporate variables and settings used during mechanical ventilatory support such as the positive end expiratory pressure (PEEP), inspiratory time to expiratory time ratio (Ti:Te), and the peak alveolar pressure (Palv). The aim is to identify a new oxygenation index for stratification of severity of ARDS

Recruitment information / eligibility
Status Completed
Enrollment 150
Est. completion date May 1, 2019
Est. primary completion date May 1, 2019
Accepts healthy volunteers
Gender All
Age group 18 Years to 65 Years
Eligibility Inclusion Criteria:

- Patients receiving mechanical ventilation in the Intensive Care Unit.

- Patients in whom the managing medical team requested an arterial blood gas (ABG) analysis.

Exclusion Criteria:

- Patients in whom arterial blood gas could not be obtained or not ordered.

Study Design

Related Conditions & MeSH terms

  • Acute Lung Injury
  • Acute Respiratory Distress Syndrome
  • Respiratory Distress Syndrome, Adult
  • Respiratory Distress Syndrome, Newborn
  • Syndrome

Intervention

Diagnostic Test:
• Obtaining arterial blood gases
Obtaining arterial blood sample

Locations
Country Name City State
Lebanon American University of Beirut Beirut

Sponsors (1)
Lead Sponsor Collaborator
American University of Beirut Medical Center

Country where clinical trial is conducted

Lebanon, 

Outcome
Type Measure Description Time frame Safety issue
Primary New oxygenation index Oxygenation index that incorporates ventilator parameters Immediate
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