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Melatonin for Prevention of Radiation Induced Oral Mucositis

Oral Mucositis (Ulcerative) Due to Radiation Clinical Trial

Official title:
The Effectiveness of Melatonin in Prevention of Radiation-induced Oral Mucositis

Clinical Trial Summary

The main aim of this study was to evaluate the effectiveness of melatonin in prevention of radiation induced oral mucositis clinically and biochemically.

Clinical Trial Description

The study was designed as randomized, controlled, clinical trial. patients who were undergoing chemoradiation were divided into two groups: Group I: was given conventional treatment. Group II: was given melatonin therapy in combination with the conventional treatment.

All patients were clinically evaluated at the start the radiotherapy, three weeks and six weeks later for pain and oral mucositis severity. in addition, the total antioxidant capacity of the melatonin was evaluated at the start of the radiotherapy and six weeks later. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03833570
Study type Interventional
Source Alexandria University
Contact
Status Completed
Phase Phase 2
Start date January 12, 2018
Completion date December 1, 2018
View Details
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