Right Ventricular Function in Heart Failure

Assessment of the RV Function in Patients With Heart Faliure Clinical Trial

Official title:

Assessment Right Ventricular Systolic Function in Heart Failure With Preserved, Reduced and Mid-range Ejection Fraction

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03641599
• Other study ID #: RV
• Status: Completed
• Start date: January 1, 2017
• Est. completion date: July 1, 2018

Study information

• Verified date: August 2018
• Source: Benha University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Only a few studies evaluated the RV systolic function in the three categories of HF, regarding the importance of understanding changes in RV function on clinical presentation and outcome; it was essential to understand the prevalence and severity of RV dysfunction among the three groups and the degree of correlation between RV with LV systolic function.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 150
• Est. completion date: July 1, 2018
• Est. primary completion date: June 1, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

Adult patients of both gender who have the followiong criteria :

(i) symptoms with or without signs of HF (ii) elevated natriuretic peptides (BNP =35pg/ mL or NT-proBNP=125pg/mL) (iii) relevant structural heart disease: left ventricle hypertrophy (left ventricular mass index =115 g/m2 for males and =95 g/m2 for females) or left atrial enlargement (>34 mL/m2) or diastolic dysfunction (E/e'=13 and a mean e' septal and lateral wall <9 cm/s) were included.

Then patients were classified according to EF into HFpEF>50%, HFrEF<40% and HFmrEF >40% and <50%

Exclusion Criteria:

Patients with chronic obstructive pulmonary disease history of pulmonary embolism patients with respiratory failure

Related Conditions & MeSH terms

• Assessment of the RV Function in Patients With Heart Faliure
• Heart Failure

Intervention

Diagnostic Test:
• echocardiography
echocardiographic assessment of the RV and LV systolic function

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
shaimaa Mostafa

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	assessment of the RV systolic dysfunction in patients with heart failure	degree and prevalence of the RV systolic dysfunction in patients with heart failure with preserved, mid-range and decreased ejection fraction	1.5 year