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The Norwegian Antibiotics for Pneumonia in Children Study — NAPiC  

Lower Respiratory Tract Infection Clinical Trial

Official title:
The Norwegian Antibiotics for Pneumonia in Children Study

Clinical Trial Summary

This study evaluates the effect of amoxicillin in the treatment of lower airway infections in preschool children. Half of the patients will receive amoxicillin, while the other half will receive placebo.

Clinical Trial Description

The overall objective of the study is to determine if antibiotic therapy is beneficial in children with pneumonia who do not have a highly suspicious bacterial infection, such as in lobar pneumonia.

Secondary objective is to determine whether antibiotic use influence the microbial flora, including antibiotic resistance, in the airways in the short or medium long term.

The study is a phase IV double-blind, placebo-controlled, multicenter, nationwide, randomized superiority trial of amoxicillin versus placebo in children aged 1-5 years of age with a lower respiratory infection. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03446534
Study type Interventional
Source Oslo University Hospital
Contact Håvard O Skjerven, PhD
Phone +47 41020249
Email h.o.skjerven@medisin.uio.no
Status Recruiting
Phase Phase 4
Start date March 7, 2018
Completion date December 2020
View Details
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