Predictive Value of Admission Blood Glucose Level in Acute Myocardial Infarction Clinical Trial
Official title:
Predictive ValueOf Admission Blood Glucose Level In Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Angioplasty
Coronary atherosclerosis is the leading cause of death worldwide. Diabetes mellitus is
associated with increased prevalence of coronary artery disease
Increased plasma glucose is a common feature in the acute phase of myocardial infarction,
even in patients without diabetes. Patients with stress hyperglycemia, but without previous
diagnosis of diabetes, were at increased risk of congestive heart failure, arrhythmia and
cardiogenic shock as well as increased both in-hospital and long-term mortality . Previous
studies have demonstrated larger infarct size and poorer prognosis inpatients with
hyperglycemia upon hospital admission compared with patients without hyperglycemia
It has been reported that stress hyperglycemia impairs microvascular circulation and may
lead to no-reflow phenomenon. No reflow phenomenon was significantly more frequent among
patients with hyperglycemia and increased progressively with increasing admission blood
glucose in patients with Acute Myocardial Infarction . Furthermore, patients with high
admission glucose are more likely to develop restenosis and require repeat revascularization
procedures compared with those with normal admission glucose and are also at increased risk
for repeated Myocardial Infarction, stent thrombosis and death.
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