Clinical Trials Logo
  1. Home
  2. Other
  3. NCT03096743

Evaluating Raised Intracranial Pressure Using MR Elastography

Idiopathic Intracranial Hypertension Clinical Trial

Official title:
Evaluating Raised Intracranial Pressure Using MR Elastography

Clinical Trial Summary

Investigators will compare magnetic resonance (MR) elastography measurements to other forms of noninvasive methods of detecting raised intracranial pressure, including optical coherence tomography (OCT) imaging measurements of the retinal nerve fiber layer (RNFL) and indirect signs of raised intracranial pressure on magnetic resonance imaging (MRI).

Clinical Trial Description

The goal of this study is to evaluate the brain elasticity in patients with idiopathic intracranial hypertension (IIH) and other forms of raised intracranial pressure, such as obstructive hydrocephalus. Investigators will evaluate for a correlation between brain stiffness and opening pressure on lumbar puncture. Investigators will also evaluate for changes in brain stiffness after interventions that are aimed at lowering intracranial pressure, including lumbar punctures, medications, and surgical interventions, such as ventriculoperitoneal shunts. Lastly, investigators will compare MR elastography measurements to other forms of noninvasive methods of detecting raised intracranial pressure, including optical coherence tomography (OCT) measurements of the retinal nerve fiber layer (RNFL) and indirect signs of raised intracranial pressure on MRI. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03096743
Study type Interventional
Source Mayo Clinic
Contact John J. Chen, M.D., Ph.D.
Phone 507-284-7140
Email chen.john@mayo.edu
Status Recruiting
Phase N/A
Start date January 10, 2017
Completion date December 2025
View Details
See also
  Status Clinical Trial Phase
Terminated NCT01863381 - Comparison of Continuous Non-Invasive and Invasive Intracranial Pressure Measurement N/A
Recruiting NCT06027567 - The Effect of an Anti-obesity Drug, Semaglutide, as Treatment in New-onset Idiopathic Intracranial Hypertension (IIH) Compared to Standard Weight Management (Dietician) With Regards to Change in Weight and Intracranial Pressure Phase 4
Active, not recruiting NCT02896452 - Astronaut Vision Issues in a Ground Analog Population: Polycystic Ovary Syndrome
Not yet recruiting NCT06059703 - Biomarkers in the Etiology of Idiopathic Intracranial Hypertension N/A
Terminated NCT05347147 - A Trial to Determine the Efficacy and Safety of Presendin in IIH Phase 3
Not yet recruiting NCT06361823 - Exploratory Study on the Efficacy and Safety of Semaglutide for Idiopathic Intracranial Hypertension Treatment Phase 3
Active, not recruiting NCT02124486 - An RCT of Bariatric Surgery vs a Community Weight Loss Programme for the Sustained Treatment of IIH N/A
Recruiting NCT02143258 - Stenting of Venous Sinus Stenosis for Medically Refractory Idiopathic Intracranial Hypertension N/A
Enrolling by invitation NCT05308823 - Outcome of Cerebral Venous Sinuses Stenting on Idiopathic Intracranial Hypertension N/A
Not yet recruiting NCT05762367 - MR Lymphatic Imaging in Idiopathic Intracranial Hypertention N/A
Completed NCT03867461 - The Effects of MAP and EtCO2 on Venous Sinus Pressures N/A
Completed NCT03963336 - Quantitative D-dimer Level and Anticoagulant Therapy in Idiopathic Intracranial Hypertension Early Phase 1
Completed NCT01003639 - Idiopathic Intracranial Hypertension Treatment Trial Phase 2/Phase 3
Completed NCT04314128 - Assessment of ICP in Idiopathic Intracranial Hypertension Using Transocular Ultrasound and Transcranial Doppler N/A
Terminated NCT03501966 - Surgical Idiopathic Intracranial Hypertension Treatment Trial Phase 3
Active, not recruiting NCT03556085 - Venous Sinus Stenting With the River Stent in IIH N/A
Completed NCT02017444 - Safety and Effectiveness of 11b-Hydroxysteroid Dehydrogenase Type 1 Inhibitor (AZD4017) to Treat Idiopathic Intracranial Hypertension. Phase 2