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Clinical Trial Summary

Chronic stroke patients exhibit gait pattern alterations which are mainly due to spasticity and treated with repetitive multifocal botulinum toxin injection(BTI). Several studies demonstrated that single BTI-session in a single muscle of paretic lower limb(LL) improved kinematic gait parameters(GP) but surprisingly none of them assessed the effects of repetitive multifocal BTI on patient's gait pattern and their duration.

The aim was to evaluate the impact of repetitive multifocal BTI-sessions on GP of chronic stroke patients. To that end, gait of patients will be compared using 3D-gait analysis after 3 consecutives BTI sessions.


Clinical Trial Description

All the patients will be treated with BTI . These injections will be performed under electrical stimulation control (~5mA). The dose, the number of site of injection per muscle is at the discretion of the physician according to patients' needs and physicians' routine clinical practice. The dilution the most commonly used will be 100 U for 2.5ml (XEOMIN®) ;


Study Design


Related Conditions & MeSH terms

  • Botulinum Toxins Injection in Stroke Patients
  • Stroke

NCT number NCT02699775
Study type Observational
Source Centre d'Investigation Clinique et Technologique 805
Contact Nicolas ROCHE, MD PhD
Phone 0033147105409
Email roche.nicolas@aphp.fr
Status Recruiting
Phase N/A
Start date December 12, 2017
Completion date December 2019