Regular HIV Testing Among At-Risk Latino Men

Human Immunodeficiency Virus (HIV) Clinical Trial

Official title:

Regular HIV Testing Among At-Risk Latino Men

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02454725
• Other study ID #: PRO00020837
• Secondary ID: R34MH100947
• Status: Completed
• Phase: N/A
• Start date: June 2015
• Est. completion date: June 1, 2018

Study information

• Verified date: January 2019
• Source: Medical College of Wisconsin
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Early HIV diagnosis followed by linkage to treatment soon after HIV infection can reduce mortality and prevent new HIV infections. To obtain the full benefit of early HIV diagnosis, the US Centers for Disease Control and Prevention suggest that high risk groups get tested for HIV regularly, every three to six months. This study will examine the feasibility of a strategy to promote regular HIV testing and HIV risk reduction among Latino men at risk for HIV which, if successful, will help to identify Latino men unaware of their HIV status, benefitting them and the society.

Description:

In the US, the HIV epidemic largely affects clusters of interconnected persons with high HIV prevalence and undiagnosed HIV infections that must be reached to reduce incidence. Latino men who have sex with men (LMSM) are overrepresented in these clusters. Following African Americans, LMSM have the highest HIV incidence rate and are the next most likely to be unaware of their HIV infection. Between 2005 and 2008, nearly one-quarter of the HIV positive LMSM were unaware of the infection.

High HIV prevalence in LMSM networks and lack of strategies to promote regular HIV testing may explain why many LMSM are not benefiting from early diagnosis. Many LMSM face social and legal challenges that hinder their access to healthcare services and outreach. They often have little understanding of HIV treatments, experience discrimination, and hold mistaken assumptions about HIV risk, including beliefs that motivate them to seek sexual partners within their high prevalence in-group as a form of preventing infection.

A social network approach can address the demands of engaging LMSM in regular HIV screening and reduce their collective risk. LMSM often rely on other LMSM who are sources of advice and referrals and who partially shield them from the double jeopardy of being a sexual and ethnic minority. Network interventions can capitalize on these relationships to promote access to resources and foster norms that reward regular testing and encourage collective safety. This project uses social networks to promote regular HIV testing and risk reduction among LMSM. Rather than delivering risk reduction messages and opportunities for HIV testing, the intervention will penetrate networks of LMSM through well positioned members. Unlike strategies that target personal networks or social groups within venues, the intervention will recruit three-ring networks of interconnected LMSM and isolate their ties. Three recruitment rings will help to find less visible LMSM; and isolating their ties will identify who can reach them. In addition to informing and motivating their peers to reduce risk, key network members will be trained to be links to prevention resources, deliver tailored prompts to HIV testing, and support peers' testing behaviors to encourage repetition.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 107
• Est. completion date: June 1, 2018
• Est. primary completion date: June 1, 2018
• Accepts healthy volunteers: No
• Gender: Male
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• self-report as a Latino man who has sex with men (LMSM);

• living in the Milwaukee area;

• willing and able to provide consent for participation;

Additional Inclusion Criteria for Social Network Seeds:

• more than 70% of social network members are LMSM

• more than 50% of LMSM social network members are at risk for HIV

Exclusion Criteria:

• Female

• 17 years of age or younger

• Unable to provide consent

Related Conditions & MeSH terms

• Acquired Immunodeficiency Syndrome
• HIV Infections
• Human Immunodeficiency Virus (HIV)
• Immunologic Deficiency Syndromes

Intervention

Behavioral:
• Social Network
Leaders of social networks will undergo small group training to develop skills to convey information effectively and deliver messages endorsing regular HIV testing to members of their social networks.
• Comparison
All participants will receive HIV counseling and rapid testing following the Wisconsin Department of Health guidelines. Sexually active men who receive a negative test result will be told that they should be HIV-tested every three to six months, unless they have a monogamous HIV negative partner

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
Medical College of Wisconsin	National Institute of Mental Health (NIMH)

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Frequency of HIV testing	Maximum number of months between two HIV tests	Twelve months post intervention
Secondary	Frequency of HIV testing	Whether the participant received an HIV test every < six months during the 12-month period following study intake	Twelve months post intervention
Secondary	HIV risk behaviors: Number of unprotected anal intercourse occasions with a non-monogamous partner	Number of unprotected anal intercourse occasions with a non-monogamous partner	Twelve months post intervention
Secondary	HIV risk behaviors: Number of sexual partners	Number of sexual partners	Twelve months post intervention