Non-arteritic Ischemic Optic Neuropathy Clinical Trial
Official title:
Pilot SINN; Assessment of Visual Field (vf)-Related Endpoints in Patients With Non-arteritic Ischemic Optic Neuropathy (N-AION)
This present research project intends to collect five quantitative test series:
- perimetric examination using static stimuli, assessing the entire (80 degree) visual
field with a fast thresholding algorithm (GATE) [Schiefer 2008] to know the extent/
magnitude of the visual field defect and its variability within the cohort and over
time
- D-BCVA, using FrACT [Bach 2007] and EDTRS chart [Ferris 1982]
- RAPD (using swinging flashlight test).
- IOP (using applanation tonometer)
- RNFT and RNFV using Spectralis OCT (star scan, ring scan 2,8 mm, and volume scan) Optic
disk morphology will be documented by fundus photography. This assessment of the
above-mentioned data is needed in order to allow for estimation of the spontaneous
course / fluctuation of the (quantified) functional and morphometric parameters of the
N-AION patients during the follow-up period. This is essential for the estimation of
the sample size of the subsequently intended SINN study, that is intended to compare
different therapeutic strategies in N-AION patients.
n/a
Observational Model: Case Control, Time Perspective: Prospective
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