Brain Lesions Following Endovascular and Surgical Treatment of Unruptured Intracranial Aneurysms

Unruptured Intracranial Aneurysms Clinical Trial

— LESUIA  

Official title:

Brain Lesions Following Endovascular and Surgical Treatment of Unruptured Intracranial Aneurysms: Incidence and Influence on Clinical Outcome in a Prospective Study.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01490463
• Other study ID #: JohannWGUH_LESUIA
• Status: Completed
• Phase: N/A
• First received: December 12, 2011
• Last updated: January 28, 2013
• Start date: August 2011
• Est. completion date: January 2013

Study information

• Verified date: January 2013
• Source: Johann Wolfgang Goethe University Hospitals
• Contact: n/a
• Is FDA regulated: No
• Health authority: Germany: Federal Institute for Drugs and Medical Devices
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to determine the incidence and impact of brain lesions in MRI after coiling and clipping of unruptured intracranial aneurysms on clinical and neurological outcome of patients.

Description:

Silent ischemic lesions after treatment of unruptured intracranial aneurysm (UIA) might alter patients' clinical and neurological outcome. Furthermore silent brain lesions are not well documented after endovascular and surgical treatment of unruptured intracranial aneurysms. Therefore, the investigators investigate the incidence and influence of treatment-related ischemic lesions in magnetic resonance / diffusion-weighted-imaging after endovascular and surgical treatment of UIA.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 0
• Est. completion date: January 2013
• Est. primary completion date: January 2013
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

• diagnosis and treatment of unruptured intracranial aneurysm

• age = 18 yrs

• written informed consent by patients prior to study participation

• willingness to participate in follow-up

Exclusion Criteria:

• ruptured intracranial aneurysm

• contraindication for MRI

• Participation in an intervention-/AMG-study

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Aneurysm
• Intracranial Aneurysm
• Unruptured Intracranial Aneurysms

Locations

Country	Name	City	State
Germany	Department of Neurosurgery, Goethe-University	Frankfurt am Main	Hessen

Sponsors (3)

Lead Sponsor	Collaborator
Johann Wolfgang Goethe University Hospitals	Department of Neurosurgery, Goethe-University Frankfurt am Main, Institute of Neuroradiology, Goethe-University Frankfurt am Main

Country where clinical trial is conducted

Germany, 

External Links

•   Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main