Clinical Trials Logo
  1. Home
  2. Other
  3. NCT00372346

Safety and Efficacy Study of Transplantation of EPCs to Treat Idiopathic Pulmonary Arterial Hypertension

Idiopathic Pulmonary Arterial Hypertension Clinical Trial

Clinical Trial Summary

Experimental data suggest that transplantation of endothelial progenitor cells (EPCs) attenuates monocrotaline-induced pulmonary hypertension in rats and dogs. In addition, clinical studies suggest that autogolous progenitor cells transplantation is feasible and safe in patients with ischemic disease. This study will investigate the feasibility, safety, and initial clinical outcome of intravenous infusion of autologous EPCs in patients with idiopathic pulmonary arterial hypertension.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00372346
Study type Interventional
Source Zhejiang University
Contact xingxiang wang
Phone 8657187236500
Email wangxx0571@yahoo.com.cn
Status Recruiting
Phase N/A
Start date June 2006
Completion date December 2007
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT01884051 - Hormonal, Metabolic, and Signaling Interactions in PAH
Completed NCT00626028 - Comparison of Inhaled Nitric Oxide and Oxygen in Participants Reactivity During Acute Pulmonary Vasodilator Testing Phase 3
Completed NCT02790450 - Acute Effects of Benzbromaron on the Pulmonary Circulation Phase 2
Recruiting NCT05584722 - Risk and Resilience in Pulmonary Arterial Hypertension and Genetically Susceptible Individuals
Not yet recruiting NCT06104228 - 129 Xenon MRI as a Biomarker for Diagnosis and Response to Therapy in Pulmonary Arterial Hypertension (PAH) Phase 2
Completed NCT01590108 - The Study of Apelin-APJ System on Pulmonary Hypertension Patients and Healthy Subjects Phase 1
Recruiting NCT05493371 - Empagliflozin in Pulmonary Arterial Hypertension Phase 2
Recruiting NCT03933579 - The PAH Platform for Deep Phenotyping in Korean Subjects
Completed NCT01613287 - Proof of Concept Study of IMMUNOadsorption Therapy in Patients With Idiopathic Pulmonary Arterial Hypertension N/A
Withdrawn NCT01645826 - Efficacy Study of Cardizem in Pulmonary Arterial Hypertension N/A
Completed NCT00641836 - Safety and Feasibility of Autologous Endothelial Progenitor Cells Transplantation in Patients With Idiopathic Pulmonary Arterial Hypertension N/A
Recruiting NCT02959723 - Physiopathology of Pulmonary Arterial Hypertension: Mechanistic Studies N/A
Recruiting NCT01288651 - Iron Deficiency In Pulmonary Hypertension Phase 4
Recruiting NCT05462574 - Right Ventricle Lipid in Pulmonary Arterial Hypertension (PAH)
Completed NCT02565030 - Chronic Thrombo-embolic Pulmonary Hypertension: Classification and Long Term Outcome
Active, not recruiting NCT01246037 - Beta-blockers in i-PAH Phase 1/Phase 2
Recruiting NCT01683981 - Exercise Capacity and Quality of Life in Patients With PPH Receiving Short Term Oral L-Citrulline Malate Phase 0
Completed NCT03069716 - A Mobile Health Intervention in Pulmonary Arterial Hypertension N/A
Completed NCT05767918 - StratosPHere (Non-interventional Study)
Completed NCT00257413 - Safety and Efficacy Study of Transplantation of EPCs to Treat Idiopathic Pulmonary Arterial Hypertension N/A