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Spironolactone Safety in Dialysis Patients

End Stage Renal Disease Clinical Trial

Official title:
Subjects With Severe Heart Failure and End-Stage Renal Disease on Hemodialysis: A Pilot Study to Assess Safety and Tolerability of Spironolactone

Clinical Trial Summary

Cardiovascular disease is the leading cause of death and disproportionately prevalent in patients with kidney disease. Spironolactone has been shown to improve survival in the general population with heart failure by up to 30%. We wish to study the safety and tolerability of aldosterone blockade with spironolactone on cardiac function in a high risk population of patients on hemodialysis. We will study and closely monitor subjects over a period of 12 months, during which they will be receiving spironolactone for a period of 6 months.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00328809
Study type Interventional
Source State University of New York - Upstate Medical University
Contact
Status Withdrawn
Phase Phase 4
Start date June 30, 2013
Completion date September 24, 2019
View Details
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