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NCT ID: NCT03357614 Completed - Clinical trials for Complicated Urinary Tract Infections

Sulopenem Followed by Sulopenem-etzadroxil/Probenecid vs Ertapenem Followed by Cipro for Complicated UTI in Adults

Start date: September 18, 2018
Phase: Phase 3
Study type: Interventional

This is a prospective, phase 3, randomized, multicenter, double-blind, double-dummy study to compare the efficacy and safety of sulopenem followed by sulopenem-etzadroxil/probenecid versus ertapenem followed by ciprofloxacin for the treatment of complicated urinary tract infections (cUTI) in adults.

NCT ID: NCT03357471 Completed - Clinical trials for Active Psoriatic Arthritis

Study to Test the Safe and Effective Use of an e-Device for the Self-injection of Certolizumab Pegol Solution by Subjects With Moderate to Severe Active Rheumatoid Arthritis, Active Ankylosing Spondylitis, Active Psoriatic Arthritis, or Moderately to Severely Active Crohn's Disease

Start date: November 3, 2017
Phase: Phase 3
Study type: Interventional

The purpose of the study is to evaluate the ability of subjects who are already prescribed Certolizumab Pergol therapy and have been self injecting with prefilled syringes for at least the previous three months, to safely and effectively self-inject Certolizumab Pegol (CZP) using the e-Device and to evaluate the post-use structural integrity of used devices and cassettes via visual examination.

NCT ID: NCT03357380 Completed - Clinical trials for Non-alcoholic Fatty Liver Disease

A Study on How Semaglutide Works on Early Stages of Scar Tissue in the Liver Assessed by Pictures of the Liver

Start date: November 28, 2017
Phase: Phase 1
Study type: Interventional

This study is looking at the effect of semaglutide on subjects with nonalcoholic fatty liver disease.This study is comparing the change in early stages of scar tissue in the liver and fat deposition in the liver in people taking semaglutide and placebo (a dummy medicine). Participants will either get semaglutide or placebo; which treatment participants get is decided by chance. Semaglutide is a medicine under clinical investigation. That means that the medicine has not yet been approved by the authorities. Participants will need to self-inject medicine once daily for 72 weeks. The medicine should be injected under the skin in the stomach, thigh or upper arm. There are about 3 weeks before participants start the study medicine and 7 weeks after you stop it. The study will last for about 82 weeks in total. Participants will have 12 clinic visits, 6 phone calls and 4 visits to an MRI centre. The study includes MRI scans of the stomach. The MRI scans will take place at a different location. Participants will be excluded from the study if the study doctor thinks that there are risks for participants health. Women cannot take part if pregnant, breast-feeding or plan to become pregnant during the study period.

NCT ID: NCT03357341 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Sensor and Electronic Health Records (EHR) Integration Pilot Study

Start date: July 23, 2018
Phase:
Study type: Observational

This is a pilot study that will evaluate the feasibility of collecting increasing amounts of clinical study data from subjects through sensor and web/app based methods and integrating it with data from their EHR to facilitate more efficient and meaningful research with acceptable quality. Approximately 100 subjects with asthma and 100 subjects with chronic obstructive pulmonary disease (COPD) will be enrolled in this prospective study. The subjects will be identified through integrated EHR records following which eligible subjects will receive study devices and training on proper use of the devices at Baseline visit. Data will be collected remotely from subject reports, devices and sensors over six months.

NCT ID: NCT03357328 Completed - Dementia Clinical Trials

Therapy Light Rooms for Improved Sleep in Dementia Patients

DEMLIGHT
Start date: September 25, 2017
Phase: N/A
Study type: Interventional

This intervention study will investigate the effect of therapy light rooms on sleep, circadian rhythms, mood, behavioural problems and function in nursing home (NH) patients with dementia.

NCT ID: NCT03357302 Completed - Clinical trials for Disability or Chronic Disease Leading to Disablement

Risk Factors Associated With the Global Burden of Disease in Reunion Island and Comparison With Mainland France and Indian Ocean Countries

AVIRON-2
Start date: December 1, 2017
Phase:
Study type: Observational

The question posed by this project is that of the regional estimate of the relative importance of the risk factors of the main pathologies. Our hypothesis is that these risk factors are of different relative importance in Reunion Island compared to metropolitan France.

NCT ID: NCT03357289 Completed - Clinical trials for Reaction - Mixed Vaccine

Mix Vaccine for Metastatic Kidney Cancer

Start date: November 30, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

The aim of this study is the safety and efficacy of mix vaccine to small metastases of kidney cancer.

NCT ID: NCT03357107 Completed - Clinical trials for Supraglottic Squamous Cell Carcinoma

Local Control After Robot-assisted Supraglottic Laryngectomy

Start date: October 1, 2016
Phase: N/A
Study type: Observational

Transoral robotic surgery is an option to treat supraglottic squamous cell carcinomas. Oncological outcomes 2 years after transoral robotic surgery for supraglottic laryngectomy were studied.

NCT ID: NCT03356821 Completed - Neonatal Stroke Clinical Trials

Perinatal Arterial Stroke Treated With Stromal Cells Intranasally

PASSIoN
Start date: February 11, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

This study will assess safety and feasibility of bone marrow-derived allogeneic MSCs, administered by the nasal route, in neonates who suffered from PAIS.

NCT ID: NCT03356678 Completed - Clinical trials for Relapsed or Refractory Peripheral T-cell Lymphoma

Pralatrexate for Relapsed or Refractory Peripheral T-cell Lymphoma

Start date: September 23, 2016
Phase: N/A
Study type: Observational

A non-interventional, multicenter, multinational retrospective analysis using electronic case report forms completed by the investigators based on information from patient medical records