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NCT ID: NCT03269864 Not yet recruiting - Clinical trials for Post Traumatic Skin Defect in Leg and Foot

Use of Perforator Flaps for Leg and Foot Reconstruction

Start date: September 5, 2017
Phase: N/A
Study type: Interventional

Perforator vessels are those where the source artery is deep and the branch that carries blood to the fasciocutaneous tissues passes through the overlying deep fascia. Soft tissue defects in the lower extremity, especially distal third of leg, present a challenge to reconstructive surgeons due to lack of reliable local flaps, conventional reconstructive options include split skin grafting, local random fasciocutaneous flaps, cross leg fasciocutaneous flap, pedicled muscular or musculocutaneous flaps or microvascular free tissue transfer. All these procedures have their limitations and associated morbidity at donor site

NCT ID: NCT03267394 Not yet recruiting - Clinical trials for Thymus and Activation Regulated Chemokine

Role of Thymus-And Activation-Regulated Chemokine (TARC) In Diagnosis Of Allergic Bronchopulmonary Aspergillosis

Start date: October 2017
Phase: N/A
Study type: Observational

This study aims to assess the value of TARC in diagnosis of allergic Bronchopulmonary Aspergillosis.

NCT ID: NCT03266978 Not yet recruiting - Clinical trials for ST Elevation Myocardial Infarction

Impact of Glycemic State on Patients ST Elevation Myocardial Infarction With Primary Percutaneous Coronary Angioplasty

Start date: January 2018
Phase: N/A
Study type: Observational

ST-elevation myocardial infarction is a major cause of morbidity and mortality worldwide. ST-elevation myocardial infarction damages the regional myocardium that undergoes ischemia and necrosis, resulting in impairment of both systolic and diastolic functions of the heart. Left ventricular function and myocardial infarct size both serve as the main determinants Of patients' outcome after myocardial infarction. Timely management of ST-elevation myocardial infarction, using reperfusion therapy, including fibrinolysis and primary percutaneous coronary intervention, leads to a better outcome for these patients.

NCT ID: NCT03266549 Not yet recruiting - Clinical trials for Large Angle Horizontal Strabismus

Botulinum Toxin Augmented Surgery vs Conventional Surgery in the Management of Large Angle Horizontal Deviations

Start date: February 20, 2021
Phase: N/A
Study type: Interventional

Horizontal strabismus includes esotropia and exotropia where there is inward or outward deviation of visual axes of the eyes respectively. The most common initial treatment of horizontal strabismus is either bilateral rectus muscle recessions or unilateral recession resection surgery. For large angle deviations (>50 prism diopters [PD]), surgery on 2 muscles alone may not be adequate with high reoperation rates. Approaches to these patients included large bilateral muscle recessions, supramaximal unilateral recession resection procedure, three or four horizontal muscle surgery, or botulinum toxin augmented surgery. Botulinum toxin augmentated strabismus surgery was reported in several studies. Owens et al.reported successful botulinum toxin augmentation of monocular recession-resection surgeries in 3 large-angle exotropia patients with successful results in two of the 3 patients. Khan reported 8 patients with > 60 PD esotropia treated with botulinum-augmented surgery. Six of 8 had deviations of 10 PD or less following surgery. Özkan et al used botulinum augmentation in a group of older patients with large angle esotropia of different etiologies, with a success rate of 57%. Lueder et al evaluated the long-term outcomes in patients with infantile esotropia. The results were good, with a 74% success rate. Based on historical comparisons, this technique appears equally as effective as 3- or 4-muscle surgery and more effective than large bilateral medial rectus recessions alone. Ideally, a prospective randomized study should be performed to more definitively determine the effectiveness of intraoperative botulinum toxin augmentation compared to surgery alone.

NCT ID: NCT03266328 Not yet recruiting - Clinical trials for ST Elevation Myocardial Infarction

Procedure and In-hospital Outcome of Patients Under 40 Years Old Undergoing Primary Percutaneous Coronary Intervention for Acute ST Elevated Myocardial Infarction in Assiut University

Start date: September 1, 2017
Phase: N/A
Study type: Observational

Sample size of 117 patients presented with ST elevated myocardial infarction for PPCI starting from september 2017 will be divided to 2 groups, group 1 age up to 40 years old and group 2 older than 40 years then previous history and clinical data and angiographic data at PPCI and follow up in-hospital and after discharge for 3 months all these data will be compared at both groups.

NCT ID: NCT03266289 Not yet recruiting - Unstable Angina Clinical Trials

Evaluation of Short Term Outcome of Different Bifurcation Stenting Techniques at Assuit University Cath. Lab

Start date: September 1, 2017
Phase: N/A
Study type: Observational

Primary aim: evaluation of the short term outcome of different techniques used in bifurcational coronary arteries intervention regarding major adverse cardiac event (MACE): cardiac death, myocardial infarction, target vessel revascularization, or stent thrombosis and occurrence of Unstable angina (UA) with ECG changes and echo findings in the same target vessel in Assiut university Cath. lab. Secondary aim: calculation of the percentage of bifurcational coronary arteries intervention in Assiut University Cath.lab

NCT ID: NCT03264950 Not yet recruiting - Cystic Fibrosis Clinical Trials

Utility of Point Shear-wave Elastography to Assess for Hepatic & Pancreatic Fibrosis in Pediatric CF Patients

CFALD
Start date: October 1, 2017
Phase: N/A
Study type: Interventional

Diagnosis of hepatic fibrosis is challenging as specific tests for detection of fibrosis in pediatric Cystic Fibrosis associated liver disease (CFALD) have not been developed and existing investigations do not correlate well with presence or severity of disease. Using a Liver biopsy it is difficult to diagnose this condition because of the patchy nature of the disease. Investigators intend to identify hepatic and pancreatic fibrosis in Cystic Fibrosis patients using Elastography and correlate this with their biochemical markers as well as histological findings of patients who have undergone liver biopsy for diagnosis of CFALD.

NCT ID: NCT03264859 Not yet recruiting - Clinical trials for STEMI - ST Elevation Myocardial Infarction

NGAL and Its Association With the No-reflow Phenomenon in ST-elevation Myocardial Infarction

Start date: September 15, 2017
Phase: N/A
Study type: Observational

The aim of this study is to investigate the association between NGAL plasma levels in ST-elevation myocardial infarction and the no-reflow phenomenon, adverse events during hospitalization and at 30-day follow-up.

NCT ID: NCT03264105 Not yet recruiting - Clinical trials for Retention Rate of Flowable Composite in Demenerlized Pits and Fissure

Retention Rate of Hydroxyapatite Nano-Fiber Reinforced Flowable Composite Versus Conventional

Start date: December 2017
Phase: N/A
Study type: Interventional

Pits and fissures have been considered as the single most important feature leading to the development of occlusal caries; About 90 % of carious lesions are found in the pits and fissures of permanent posterior teeth .Several materials and techniques have been developed to enhance the longevity of pit-and-fissure sealants, including the use of flowable composite resins as pit-and-fissure sealants

NCT ID: NCT03263468 Not yet recruiting - Clinical trials for ST Elevation Myocardial Infarction

Revascularization StrategIes for ST Elevation Myocardial Infarction Trial

ASSIST-MI
Start date: September 1, 2017
Phase: N/A
Study type: Interventional

This study is being conducted in patients with a major heart attack caused by a blocked artery undergoing Percutaneous Coronary Intervention (PCI) to open up the blockage. Up to 50% of people with an heart attack are found to have one or more additional narrowings that did not cause the heart attack. At present the best way to manage these additional blockages is not known. Many cardiologist recommend opening these blockages at at a later time after the heart attack. The present study is examining if PCI of all blockages at the same time as the PCI for the artery that caused the major heart attack (SS-PCI) will reduce the amount of heart damage compared to performing PCI of additional blockages 2-45 days later (IRA-PCI). Clinical follow up will be completed at 3, 12 and 24 months to determine heart function and monitor adverse events.