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NCT ID: NCT04727372 Completed - Clinical trials for Social Acceptance, Social Anxiety

Social Acceptability of COVID-19 Vaccines in Pakistan

Start date: January 23, 2021
Phase:
Study type: Observational [Patient Registry]

Social settings of Pakistan is unique in the sense that it is composed of multilingual, multicultural and different ethnicities. Also their believes and faiths are so unpredictable. It is therefore observed that this social phenomenon affects the acceptability of new things in this area. Polio vaccination has not worked so well in the past. Iodized salt acceptability has also been criticized in the last decades and is a matter of controversy till now. This behavior has also developed before the commencement of vaccination of COVID-19 in Pakistan, as there are many rumors and fears circulating via social media amongst Pakistan. What will be the acceptance rate for this vaccination, the time will decide.

NCT ID: NCT04726644 Completed - Clinical trials for Ventral Hernias in Cirrhotic Patients

Evaluation of Surgical Techniques in Cirrhotic Patients With Ventral Hernias

Start date: January 1, 2017
Phase:
Study type: Observational [Patient Registry]

ventral hernias are defects of the anterior abdominal wall, which can be congenital or acquired including epigastric, umbilical and incisional hernia. Umbilical hernias represent a common surgical problem in cirrhotic patient with ascites with 20% incidence. This work was deigned to assess outcome of different techniques of closure of ventral hernias in cirrhotic patients.

NCT ID: NCT04726540 Completed - Clinical trials for Patient Satisfaction Using Implant Retained Overdentures

A Seven-year Follow-up Study of Patient Satisfaction With Three-Implant-Retained Mandibular Overdentures

Start date: January 12, 2013
Phase:
Study type: Observational [Patient Registry]

Purpose: This study aimed to compare patients' satisfaction with mandibular overdentures retained by three-splinted implants and conventional complete dentures during a seven-year follow-up period. Materials and Methods: Thirty edentulous male patients (mean age: 60 years) were carefully selected and divided into two equal groups. All patients received a new set of complete dentures. (Group I) patients received three implants in the anterior mandible and were connected after three months with bars, clips and loaded. (Group II) patients' received conventional complete dentures. Patients' satisfaction was recorded for both groups at three weeks (baseline) and after 1, 3, 5 and 7 years. Patients were then asked to grade their overdentures/dentures on a visual analog scale and written questionnaire to evaluate their overall satisfaction. Results: satisfaction scores of Group I patients was found to be statistically significantly higher than that of Group II patients (p < .05) at 3, 5 and 7 years follow-up, meanwhile no statistically significant difference was found at baseline or after 12 months. Conclusions: The long-term results suggest that three implants-retained mandibular overdenture with a clip-bar attachment appears to be a successful rehabilitation strategy which is superior to conventional dentures for patients with advanced ridge resorption.

NCT ID: NCT04726436 Completed - Clinical trials for Postoperative Nausea and Vomiting

Dextrose Effect on Postoperative Nausea and Vomiting (PONV)

Start date: January 25, 2021
Phase: N/A
Study type: Interventional

The aim of this study to assess which time and dose of dextrose solution more effective in decreasing postoperative nausea and vomiting.

NCT ID: NCT04726280 Completed - Clinical trials for Extrafascial Interscalene Plexus Brachial Block

Respiratory Impact of LA Volume After IS Block

Start date: February 1, 2021
Phase: Phase 4
Study type: Interventional

The hypothesis of this study is that a reduced extrafascial volume of local anesthetic for an interscalene brachial plexus block is associated with a lower incidence of diaphragmatic hemiparalysis after an arthroscopic surgery of the shoulder, without any reduction of the analgesic efficacy.

NCT ID: NCT04726202 Completed - Clinical trials for Healthcare Common Procedure Coding System

Impact of Semi-automated Proposal and Optimization of Diagnoses and Surgical Procedures for Precoding: a Randomized Controlled Trial

Start date: June 1, 2019
Phase:
Study type: Observational

The hypothesis of present study is that the daily monitoring and optimization of DRG coding is associated with higher reimbursement. Therefore, the primary objective is to determine if the daily monitoring and optimization of DRG coding of individual cases leads to better proceeds per day.

NCT ID: NCT04725123 Completed - Clinical trials for Clostridioides Difficile Infection

Addressing Personalized Needs in Clostridioides Difficile Infection

BEYOND
Start date: January 26, 2021
Phase: N/A
Study type: Interventional

BEYOND is aiming to demonstrate how by enrichment of the available SPECIFY score, patients at great likelihood for CDI with unfavorable outcome are early detected

NCT ID: NCT04725084 Completed - Clinical trials for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

Comparison of Non-invasive Oxygenation Strategies in Patients Admitted for Covid-19 Acute Respiratory Distress Syndrome

SONIC-19
Start date: July 1, 2020
Phase:
Study type: Observational

Acute Respiratory Distress Syndrome (ARDS) is the main clinical presentation of SARS-CoV-2 (Covid-19) infected patients admitted in Intensive Care Unit (ICU). During the first phase of the outbreak (between February and May 2020), the use of invasive Mechanical Ventilation (MV) was largely required with 63% of ICU patients intubated in the first 24 hours after admission and up to 80% of patients during the overall ICU stay. Mortality was especially higher when using MV in the first 24 hours. In contrast, the use of non-invasive oxygenation strategies in the first 24 hours was only 19% for High Flow Nasal Cannula oxygen therapy (HFNC) and 6% for Non-Invasive Ventilation (NIV). Several non-invasive oxygenation strategies were proposed in order to delay or avoid MV in ICU patients suffering from Covid-19 ARDS. The use of HFNC became the recommended oxygenation strategy, based in particular on publications prior to the outbreak. The use of NIV or Continuous Positive Airway Pressure (CPAP) combined with HFNC have also been proposed. Although these non-invasive oxygenation strategies seem widely used in the second phase of the outbreak, they have not yet confirmed their clinical impact on MV requirement and patient's outcome. Moreover, no comparison has been made between these different non-invasive oxygenation strategies. The aim of this study is to compare different non-invasive oxygenation strategies (HFNC, NIV, CPAP) on MV requirement and outcome in ICU patients treated for ARDS related to Covid-19.

NCT ID: NCT04724525 Completed - Clinical trials for Visual Acuity Reduced Transiently

Changes in Power and Cylinder Axis of Toric Soft Contact Lenses (LKL)

Start date: November 17, 2020
Phase: N/A
Study type: Interventional

Astigmatism is a common refractive error resulting from a toric-surfaced cornea which using a toric soft contact lens could be one of the therapy options. Due to the numerous possible combinations between sphere powers, cylinder powers, and cylinder axes, manufacturers of disposable soft toric contact lenses limit their toric lens range, while still aiming to cater to the majority of astigmatic patients. Due to that reason, the possibility of astigmatism patients getting a different combination of power and axis with toric soft contact lenses sold on the market will be high due to SKU limitations. This research aims to ascertain the impact of altering cylinder power and axis on visual quality and convenience in astigmatism participants using toric soft contact lens. The study was conducted at Kirana Ciptomangunkusumo Hospital, Jakarta, starting in April 2020. The study is a prospective, randomized, participant-masked, crossover clinical trial where the participants were tested for the following conditions on different days using full spherocylinder correction and under-correction by 0.25, 0.50, and 0.75 DC while maintaining spherical equivalence. Axis was also misaligned between -30° and +30°, in 10° steps. For each visit, the patient was examined visual acuity, contrast visual acuity using the Pelli-Robson, and assessed patient comfort using the VAS method.

NCT ID: NCT04724096 Completed - Clinical trials for Head and Neck Squamous Cell Carcinoma

Evaluation of OE-MRI in Patients With H&N Cancer

Start date: March 4, 2021
Phase:
Study type: Observational

Assessment of the use of oxygen enhanced MRI scanning in a cohort of patients with head and neck squamous cell carcinomas to identify areas of hypoxia with tumours and relate this to treatment outcomes.