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NCT ID: NCT04763590 Completed - Anxiety Clinical Trials

Cognitive Behavioral Therapy for Mechanical Ventilation Wean

Start date: November 29, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to use CBT strategies in assisting patients hospitalized in intensive care units in ventilation wean through a case series of 2 patients.

NCT ID: NCT04763421 Completed - Clinical trials for Upper GI; Lower GI; Gynecological

A Prospective, Single-Arm Multi-Center Study of the ENSEAL X1 Curved Jaw Tissue Sealer in Select Procedures

Start date: April 22, 2021
Phase: N/A
Study type: Interventional

This prospective, single-arm, multi-center study will collect clinical data in a post-market setting by procedure group (upper gastrointestinal [GI], lower GI, and gynecological). Investigators will perform each procedure using the device in compliance with their standard surgical approach and the ENSEAL X1 Curved Jaw and Generator G11 instructions for use.

NCT ID: NCT04763395 Completed - Clinical trials for Liver Function Tests Abnormalities

Liver Function Test Abnormalities in COVID-19

COVID-19
Start date: January 29, 2021
Phase:
Study type: Observational

With the increasing number of COVID-19 infected patients, several studies reported that the liver is the most frequently affected organ after lung damage. The percentage of infected patients who had abnormal levels of transaminases (alanine aminotransferase (ALT) and aspartate aminotransferase (AST)) was about 14.8-53.1%. The elevation in serum bilirubin was mostly mild. Aims of work: - To study liver function tests abnormalities in Egyptian patients who infected with COVID19 - To evaluate if liver function test abnormalities are related to the severity of the Covid19.

NCT ID: NCT04763096 Completed - Clinical trials for Evidence of Liver Transplantation

Evaluate the Efficacy and Safety of the ADVAGRAF®

STABLE
Start date: November 2016
Phase: Phase 4
Study type: Interventional

The primary objective of this study is to evaluate the efficacy of 6-month treatment with Advagraf® converted from 12-month treatment with tacrolimus in stable liver transplant recipients. The secondary objective of this study is to evaluate severity of acute rejection confirmed by biopsy in 24 weeks, incidence of chronic rejection, patient and graft survival rates in 24 weeks, incidence of adverse events, blood pressure, tacrolimus trough level, drug compliance, and adherence.

NCT ID: NCT04762719 Completed - Diabetes Clinical Trials

PET Imaging to Delineate Macrophage Activation in Diabetic Gastroparesis

Start date: May 10, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

Macrophage-driven immune dysregulation has been shown to be involved in pathophysiology of diabetic gastroparesis. Currently, there are no non-invasive ways to study macrophage activation in humans. The researchers are trying to determine the utility of 11C-ER176 based PET-CT scanning to determine pro-inflammatory macrophage activation in gastric wall of patients with diabetic gastroparesis.

NCT ID: NCT04762615 Completed - Immunosuppression Clinical Trials

Impact of Underlying Renal Disease and Immunosuppressive Regimen on Ovarian Reserve in Renal Patients

Start date: June 1, 2018
Phase:
Study type: Observational [Patient Registry]

Aging, renal pathology (eg SLE, ADPKD), X-ray exposition and pharmacological treatments, especially previous strong immunosuppression, may negatively influence the ovarian reserve in childbearing age women. Anti-Müllerian hormone (AMH) is regarded as biomarker for ovarian reserve. Every female with renal disease regularly menstruating that met exclusion criteria could have participated. The aim was to assess ovarian reserve in female patients with normal menstrual cycle and kidney disease, including kidney transplant recipients.

NCT ID: NCT04762563 Completed - Low Back Pain Clinical Trials

Effect of Treatment on Connective Tissue in Low Back Pain

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

The purpose of the study is to investigate the effects of instrument assisted soft tissue mobilization (IASTM) and kinesiology taping (KT) that are additional treatment to the conservative treatment for the lumbar region and hamstrings and connective tissue thickness in patients with chronic non-specific low back pain (CNSLBP).

NCT ID: NCT04762420 Completed - Anesthesia Clinical Trials

Sugammadex Dosing: Anaesthesiologist Clinical Perception Versus Quantitative Monitoring

Start date: February 1, 2019
Phase:
Study type: Observational

Many clinicians continue to rely on subjective evaluation in making decisions about the adequacy of neuromuscular function before tracheal extubation rather than using quantitative monitoring. The aim was to compare the sugammadex dose as suggested by senior anaesthesiologists (SSD) based on clinical experience versus the dose determined by quantitative monitoring (QSD) to determine if the subjective dose was appropriate.

NCT ID: NCT04762316 Completed - Clinical trials for Uterine Fibroids Affecting Pregnancy

Composition for Treating Uterine Fibroid (PP6)

PP6
Start date: January 1, 2019
Phase: N/A
Study type: Interventional

Pregnenolone & Pyridoxal Phosphate (PP6) for treating uterine fibroids in women pregnancy to lost the size fibroids and to dissolve fibroids. Uterine fibroids are a very common finding in women pregnancy of reproductive age, fibroids fast grow in the first trimester pregnancy. PP6 against the rapid growth of fibroids under the influence of hormones during pregnancy. Use to PP6 think about regulating stable Oestrogen level and to dissolve fibroids. This is a substantial insight into the pathogenesis of disease, with a clear path toward clinical application, or which would lead to a substantial advance and perfect in management or public health policy.

NCT ID: NCT04762056 Completed - Covid19 Clinical Trials

CPAx for Assessing Functional Status of COVID-19 Patients After Intensive Care Unit Discharge

Start date: February 22, 2021
Phase:
Study type: Observational

The present assessment tools for assessing physical function after intensive care unit (ICU) can be categorized as (1) functional tests (2) walk tests (3) strength test (4) Health-related quality of life (HRQOL). Strength tests such as Medical Research Council Scale and HRQOL (e.g. Short form-36 (SF-36) tests may require awakening and appropriate mental health. However, mental impairments were seen in a considerable number of patients (2). Walk tests such as Six-Minute Walk Test (6MWT) or Timed Up&Go (TUG) can be impractical, some patients could not be able to perform these due to severe impairment. These tests require space to perform and may require management of several drips, drains, and oxygen delivery systems while the patient is walking and turning which render the test difficult to carry out. Among these three specific tools, CPAx seems to be the assessment tool that can be considered easy to use in the clinical setting due to the short time required for assessment and relatively minimal use of equipment (hand dynamometer for grip strength measurement). This study aims to investigate validation of Chelsea Critical Care Physical Assessment Tool in the assessment of the functional status of COVID patients discharged from ICU and investigate the feasibility of commonly used assessment tools for assessing physical function after ICU in COVID patients discharged from ICU.