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NCT ID: NCT04855994 Completed - Clinical trials for Postoperative Analgesia

Comparison of Thoracic Paravertebral Block and Pectoral Nerve Block

Start date: June 28, 2017
Phase: N/A
Study type: Interventional

This study aims to compare the efficacy and safety of ultrasound-guidedPECS II block with TPVB for postoperative analgesia after VATS.

NCT ID: NCT04855097 Completed - Clinical trials for Acute Decompensated Heart Failure

Evaluation of Blood Volume Analysis- Guided Management of Decompensated Heart Failure

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

Diuretic therapy is first-line treatment for acute decompensated heart failure. However, accurate assessment and management of patient blood volume is challenged by the limitations of physical exam and surrogate markers for blood volume. The study primary objective is to determine if goal-directed care as quantified by direct Blood Volume Analysis (Daxor BVA-100™) in addition to usual care results in more appropriate treatment and consistent achievement of euvolemia.

NCT ID: NCT04854837 Completed - Covid19 Clinical Trials

Safety of Remdesivir Treatment in COVID-19 Patients Requiring Hemodialysis

REM-HD
Start date: April 12, 2021
Phase:
Study type: Observational

The FDA approved the antiviral drug remdesivir for use in adults for the treatment of COVID-19 requiring hospitalization. There are only limited data about the safety of the drug in hemodialysed patents. Chronic kidney disease is a risk factor in COVID-19 for developing severe disease. The aim of our investigation is to observe the safety of remdesivir among hemodialysed patients requiring hospitalization for COVID-19. We are going to compare two group's data: 1. Hemodialysed COVID-19 patients requiring hospitalization because of pneumonia and need of oxygen supplementation, and admitted after 12/Apr/2021 - these patients received remdesivir. 2. Hemodialysed COVID-19 patients requiring hospitalization because of pneumonia and need of oxygen supplementation, and admitted before 12/Apr/2021 - these patients did not receive remdesivir.

NCT ID: NCT04853641 Completed - Clinical trials for Perioperative/Postoperative Complications

Impact of Age and BMI on Liver Transplant Outcomes

Start date: July 1, 2020
Phase:
Study type: Observational

Prospectively enrolled retrospective chart review and Liver Transplant database review to determine the modifiable and nonmodifiable risk factors specifically relating to Living Donor Liver Transplants. To observe the impact of age and BMI on graft outcomes and whether they impact the intraoperative management, post-operative length of stay, and complications.

NCT ID: NCT04853290 Completed - Pain Clinical Trials

Patient Experience in Peripheral Venipuncture With and Without Ultrasound

PERCEPT
Start date: September 23, 2021
Phase: N/A
Study type: Interventional

Randomized clinical trial to compare the patient's experience after peripheral venipuncture catheterization using the conventional technique (vein visualization and palpation) versus ultrasound-guided venous puncture. Patients with indication of peripheral venous puncture, admitted to the clinical inpatient units on the hospital where the study will be conducted (Hospital de Clinicas de Porto Alegre - HCPA) will be enrolled in this single-center trial and will be randomized to conventional peripheral venipuncture performed by a registered nurse; or ultrasound-guided peripheral venipuncture performed by a registered nurse with expertise in vascular access.

NCT ID: NCT04853277 Completed - Multiple Myeloma Clinical Trials

Patient Reported Outcomes and Patient Education in Cellular Therapy Patients

Start date: February 7, 2021
Phase: N/A
Study type: Interventional

The purpose of this research is to provide an educational visit addressing common emotional stressors involved in the transplant/CAR-T process, and determine if this added education improves levels of anxiety, depression, and fatigue after transplant/CART in comparison to people who do not receive the brief educational visit.

NCT ID: NCT04853264 Completed - Ultrasonography Clinical Trials

Ultrasound Guided Peripheral Catheterization Increases First-attempt Success Rate

SPECTRA
Start date: September 23, 2021
Phase: N/A
Study type: Interventional

Randomized clinical trial to test the assertiveness on the peripheral vein puncture attempt by comparing two methods: peripheral venipuncture catheterization using the conventional technique (vein visualization and palpation) versus ultrasound-guided venous puncture. Patients with indication of peripheral venous puncture, admitted to the clinical inpatient units on the hospital where the study will be conducted (Hospital de Clinicas de Porto Alegre - HCPA) will be enrolled in this single-center trial and will be randomized to conventional peripheral venipuncture performed by a registered nurse; or ultrasound-guided peripheral venipuncture performed by a registered nurse with expertise in vascular access.

NCT ID: NCT04853238 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Chronic Obstructive Pulmonary Disease (COPD) Maintenance Treatment Patterns in China

Start date: April 27, 2021
Phase:
Study type: Observational

This observational study will be conducted in COPD participants in Tier 2 and 3 hospitals in China to gain an understanding of the complex COPD management and physician's treatment strategy.

NCT ID: NCT04853199 Completed - Clinical trials for SARS (Severe Acute Respiratory Syndrome)

Quercetin In The Treatment Of SARS-COV 2

QUERCOV
Start date: June 1, 2021
Phase: Early Phase 1
Study type: Interventional

In 1937, Albert Szent-Gyorgyi received a Nobel Prize for discovering vitamin C and flavonoids, as well as for exploring their biochemical properties. Originally, he gave the flavonoids the name "vitamin P" because of their effectiveness in reducing the permeability of blood vessels. This name was abandoned when it was realized that these substances were not really vitamins. Quercetin is extracted from a variety of plant sources, including the onion peel and the seeds and pods of Dimorphandra mollis, a legume tree native to South America. Although we are far from knowing everything about quercetin, its antioxidant, anti-inflammatory, and antihistamine (antiallergic) properties have been observed in numerous in vitro and animal studies.

NCT ID: NCT04853147 Completed - Clinical trials for C.Surgical Procedure; Gastrointestinal

Triple Therapy for Postoperative Nausea and Vomiting in Laparoscopic Gastrointestinal Surgery

Start date: April 27, 2021
Phase: Phase 3
Study type: Interventional

Postoperative nausea and vomiting (PONV) are common in patients, especially in patients at high risk. PONV may result in prolonged hospital stay and threaten patients' life. Because the etiology of PONV is very complex, there is an increasing focus on combining antiemetics from different classes for PONV prophylaxis. Fosaprepitant is a neurokinin-1 (NK-1) receptor antagonist to prevent PONV. Palonosetron is a 5-HT3 receptor antagonist with high efficacy and sustained action for PONV prophylaxis. Dexamethasone belongs to corticosteroid and also has the ability to reduce the incident of PONV. This study aims to use the combination of these three drugs in high-risk patients to test whether triple therapy is better than combination of palonosetron and dexamethasone to prevent PONV.