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NCT ID: NCT05325216 Not yet recruiting - Clinical trials for Urinary Incontinence

Urinary Continence of Female POPRC and OIN

Start date: April 2022
Phase: N/A
Study type: Interventional

To compare the urinary continence rate and long-term oncological outcomes of pelvic-organ preserving radical cystectomy (POPRC) with orthotopic ileal neobladder (OIN) versus standard radical cystectomy(SRC) with OIN.

NCT ID: NCT05323877 Not yet recruiting - Clinical trials for Large Hole Percutaneous Arterial Closure

Safety and Performance Study of Large Hole Vascular Closure Device - France

FRONTIER V
Start date: May 2022
Phase: N/A
Study type: Interventional

This study will be a prospective, multi-centred, non-randomized study to investigate the safety and performance of the PerQseal® + in up to 20 patients in 2 centres within France. The PerQseal® + shall be indicated for the percutaneous closure of femoral artery punctures and to induce arterial haemostasis in patients undergoing endovascular procedures requiring an arteriotomy created with 14 - 22 F sheaths (arteriotomy up to 26 F).

NCT ID: NCT05322460 Not yet recruiting - Clinical trials for Long-term Effects Secondary to Cancer Therapy in Adults

Web-based Intervention for Long-term Breast Cancer Survivors

CUMACA-M
Start date: January 2023
Phase: N/A
Study type: Interventional

The number of breast cancer survivors is growing. More cured women are becoming long-term survivors of breast cancer (LS-BC) at least 5 years after diagnosis and after treatment has been completed. Some of these LS-BC return to daily life without any problems; however, in many cases, they experience and have to deal with physical sequelae (chronic fatigue, pain, etc.) psychological sequelae (anxiety, depression, fear of recurrence, etc.) and social sequelae (altered interpersonal relationships, difficulty in returning to work, etc.). For many LS-BC, these health problems are not being met by health professionals. Thus there is a need to promote greater continuity and coordination between specialized oncology care and primary health care in order to enhance specific follow-up of these women in the community. However, the role of the primary health care team in the provision of care in the long-term cancer survival is not clearly defined and few actions have been aimed at improving care activities, standardizing procedures and protocols, developing documentation and registries and updating the training of health care professionals. Therefore, this study aim to design, implement, and evaluate a web based tailored intervention, using artificial intelligence, to improve the quality of life of long-term breast cancer survivors, and self-efficacy for the management of late sequelae from primary care.

NCT ID: NCT05320172 Not yet recruiting - Dry Eye Clinical Trials

Platelet Rich Plasma in Corneal Surface Diseases

Start date: June 2023
Phase: Phase 3
Study type: Interventional

The Aim of the study is to evaluate the efficacy of platelet rich plasma eye drops in the management of different corneal surface disorders. PRP is a blood sample with a concentrated platelet count, and numerous growth factors that are associated with conjunctival and corneal wound healing process. which is an important advantage over other products. PRP eye drops recently are proving to be an effective and potent therapeutic approach to promote corneal wound re-epithelization and promote ocular surface regeneration in different pathological conditions.

NCT ID: NCT05318729 Not yet recruiting - Postoperative Pain Clinical Trials

Use of a Vibration Tool for Postoperative Pain Control in Distal Radius Fractures

Start date: March 2025
Phase: N/A
Study type: Interventional

The purpose of this research study is to determine if using a vibration tool improves pain control after surgical treatment of distal radius fracture. Additionally, the investigators would like to determine if this tool has any impact on consumption of pain medications postoperatively.

NCT ID: NCT05317585 Not yet recruiting - Clinical trials for Pregnancy, High Risk

Continuous Glucose Monitor Use in Pregnancy

Start date: October 1, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to perform a randomized controlled trial among 180 pregnant women with type 2 diabetes mellitus (T2DM) comparing continuous glucose monitor (CGM) use to the standard of care of multiple daily fingerstick glucose monitoring and its impact on large for gestational age infants, maternal glycemic control, patient satisfaction, and additional adverse perinatal outcomes.

NCT ID: NCT05317351 Not yet recruiting - Adenoma Clinical Trials

A Prospective Randomized Study Comparing the Adenoma Detection Yield of SC, AI and Combined AI and G-EYE®

Start date: May 2022
Phase: N/A
Study type: Interventional

This is a multicenter, 3-arm, randomized, open-label study. Subjects referred to colonoscopy for screening or surveillance will be randomized in a 2:5:5 into one of the following arms: (i) Standard Colonoscopy (ii) Artificial Intelligence Aided Colonoscopy (GI Genius™) (iii) Combined Artificial Intelligence Aided Colonoscopy (GI Genius™) and G-EYE® Balloon Aided Colonoscopy

NCT ID: NCT05317325 Not yet recruiting - Clinical trials for Esophageal Squamous Cell Carcinoma

A Translational Study of Tumor Antigen-pulsed DC Vaccine for ESCC

Start date: April 1, 2022
Phase: Phase 1
Study type: Interventional

The aim of this single center, single arm and prospective study is to explore the safety and efficacy of tumor antigen-pulsed DC vaccine( OCDC and NeoDC) for postoperative adjuvant treatment of ESCC

NCT ID: NCT05315388 Not yet recruiting - Anxiety Clinical Trials

Effects of "Vitamin N" Nature Immersion Therapy on Stress Levels in Health Care Workers in the City of Bogotá

Start date: October 15, 2022
Phase: N/A
Study type: Interventional

Recent studies on health personnel in Colombia have evidenced the considerable increase in the levels of stress and anxiety, among other psychological disorders, as a product of the COVID-19 pandemic that is being experienced since 2019 and that implies a greater demand for attention from the affected citizens, with the consequent work overload and tension due to the risk of contagion. Thus, the present work will allow the generation of new knowledge in relation to the benefits of Vitamin N therapy in Colombia; which can contribute quickly and effectively to the reduction of stress levels, anxiety, insomnia, and depression in individuals, when compared with conventional interventions and result in possible benefits such as the reduction of health problems such as obesity, diabetes, high blood pressure, and diseases associated with the immune system.

NCT ID: NCT05315336 Not yet recruiting - Clinical trials for Hemophagocytic Lymphohistiocytosis

L-DEP/DEP Regimen and PD-1 Antibody as a Treatment for Relapse/Refractory EBV-HLH

Start date: June 1, 2022
Phase: Phase 3
Study type: Interventional

This study aimed to investigate the efficacy and safety of L-DEP (L-Asparaginasum, liposomal doxorubicin, etoposide and methylprednisolone) together with PD-1 antibody as an treatment for relapse/refractory EBV associated hemophagocytic lymphohistiocytosis.