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Osteoarthritis clinical trials

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NCT ID: NCT04660071 Completed - Clinical trials for Osteoarthritis, Knee

Ultrasound Imaging of Quadriceps Muscle in Patients With Knee Osteoarthritis

Start date: September 18, 2020
Phase:
Study type: Observational

Echo intensity (EI) assessment using ultrasonography helps monitoring disease-induced muscle quality changes. However, there are no study investigating the reliability of EI in patients with knee osteoarthritis (OA). The primary aim of the present study was to investigate the inter and intra-rater reliability of EI evaluation by grayscale histogram analysis of quadriceps femoris muscle in patients with knee OA. The second aim was to compare the mean grayscale values obtained using both the Free Hand Tool (FHT) and Rectangular Marquee Tool (RMT) methods in ImageJ. Thirty patients with knee OA were included in this cross-sectional study. The echogenicity measurements of the Rectus Femoris, Vastus Inter-medius, Vastus Lateralis and Vastus Medialis were performed by two different researchers. Reliability analysis of EI measurements were calculated with using intraclass correlation coefficient (ICC), standard error of measurement (SEM) and coefficient of variation (CV) and Bland and Altman plot analysis.

NCT ID: NCT04657926 Completed - Osteoarthritis Clinical Trials

A Trial of APPA in the Treatment of Knee Osteoarthritis

Start date: September 9, 2020
Phase: Phase 2
Study type: Interventional

A placebo controlled study of APPA in 150 participants with Osteoarthritis of the knee

NCT ID: NCT04654871 Completed - Osteoarthritis Clinical Trials

Effects of Glucosamine and Chondroitin Sulfate Supplementation in Addition to Resistance Exercise Training and Manual Therapy in Patients With Knee Osteoarthritis

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

Osteoarthritis (OA) IS one of the most common joint disorders, affecting not only the joints but also the surrounding muscles, which become weak. Resistance exercise reduces pain and improves function in patients with OA of the knee. Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used by patients with OA to reduce pain and thereby maintain the ability to perform daily activities. However, there is accumulating evidence for a negative effect of NSAIDs, thus many patients with OA are treated with dietary supplementations such as glucosamine and chondroitin sulfate, and some studies show a beneficial effects on cartilage and pain. However, their effect on OA symptoms and cartilage remains controversial. Thus, it is important to investigate whether a potentially beneficial effect of glucosamine and chondroitin sulfate with resistance exercise and manual therapy in patients with knee OA.

NCT ID: NCT04653090 Completed - Osteoarthritis Clinical Trials

Varus Stem Positioning of a Cementless Anatomical THA. (VARABG)

VARABG
Start date: January 1, 2018
Phase:
Study type: Observational

Varus positioning is the most common femoral malposition in total hip arthroplasty (THA). The aim of this study was to compare the long-term results of an anatomical cementless femoral stem positioned in varus with those in neutral alignment.

NCT ID: NCT04648956 Completed - Knee Osteoarthritis Clinical Trials

Arabic Version of the ICOAP Questionnaire

Start date: October 25, 2020
Phase:
Study type: Observational

A study to translate and cross-culturally adapt the Intermittent and Constant Osteoarthritis Pain (ICOAP) measurement tool into the Arabic language, and assess its psychometric properties.

NCT ID: NCT04648072 Completed - Knee Osteoarthritis Clinical Trials

How Does the Addition of Adductor Canal Block to Local Infiltration Affect Recovery in Patients Undergoing Total Knee Arthroplasty? A Feasibility Study.

TRUE KnORTH
Start date: November 4, 2020
Phase: N/A
Study type: Interventional

The use of periarticular injection and adductor canal block are well-established techniques used both in combination or in isolation in the management of postoperative pain for patients undergoing total knee arthroplasty. The aim of this study is to investigate whether combining these two techniques have an added benefit, compared to periarticular injection alone, with respect to quality of recovery, functional return, discharge readiness, and short and long term post-operative narcotic use.

NCT ID: NCT04645238 Completed - Knee Osteoarthritis Clinical Trials

Comparison of the Effects of Static and PNF Hamstring Stretching Exercises in Patients With Knee Osteoarthritis

Start date: September 1, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to determine and compare the effects of static and PNF hamstring stretching exercises on joint pain, hamstring flexibility and functional status in patients with knee osteoarthritis.

NCT ID: NCT04641546 Completed - Clinical trials for Osteoarthritis Shoulder

Effectiveness of Occupation-Based Intervention Compared With Therapeutic Exercise for Older Adults With Shoulder OA.

Start date: October 28, 2019
Phase: N/A
Study type: Interventional

As a registered and licensed occupational therapist, I completed a six-week evidence based research study to determine the effects of occupation-based intervention and therapeutic exercises versus therapeutic exercises alone.

NCT ID: NCT04640974 Completed - Clinical trials for Osteoarthritis, Ankle

Study of Cingal® for Symptomatic Relief of Osteoarthritis of Ankle Joint

Start date: January 14, 2021
Phase: N/A
Study type: Interventional

This Trial will obtain clinical data to support an expanded indication for a single injection of Cingal® used for the symptomatic relief of osteoarthritis in the ankle joint.

NCT ID: NCT04640961 Completed - Clinical trials for Osteoarthritis, Shoulder

Study of Cingal® for Symptomatic Relief of Osteoarthritis of Shoulder Joint

Start date: January 16, 2021
Phase: N/A
Study type: Interventional

This Trial will obtain clinical data to support an expanded indication for a single injection of Cingal used for the symptomatic relief of osteoarthritis in the shoulder joint.