Ocular Hypertension (OHT) Clinical Trial
Official title:
A Double-masked, Placebo-controlled, Dose-escalation Study and Double-masked, Two-sequence, Crossover Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ONO-9054 in Patients With Ocular Hypertension or Mild Open-Angle Glaucoma
The primary objective of this study is to evaluate the safety and tolerability of 3 planned
doses of ONO-9054 in the eyes of adult male and female patients with ocular hypertension
(OHT) or mild open angle-glaucoma (OAG).
The secondary objectives are to evaluate Pharmacodynamics (PD) and to characterize the
pharmacokinetic (PK) profile of ONO-9054 and its metabolite in plasma and to compare its
tolerability following morning and evening dosing.
n/a
Allocation: Randomized, Endpoint Classification: Pharmacokinetics/Dynamics Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
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