Obesity Clinical Trial
Official title:
Effect of Soleus Muscle Push Ups on Oxidative Stress and Inflammatory Markers, Soleus Endurance, and Adipocytokines Between Type 2 Diabetic, Overweight/Obese and Normal Weight Individuals.
The study aims to investigate the impact of Soleus Push Ups (SPU) on Soleus Muscle endurance, Oxidative Stress Markers, Inflammatory markers and Adipocytokines among people in the United Arab Emirates. This will be a pre-post intervention study with participants divided into three groups: Lean normal metabolic profile, metabolically healthy overweight/obese, and patients with Type 2 Diabetes Mellitus. Assessment of anthropometry and body composition, Soleus Muscle Endurance, blood tests for Inflammatory Markers, Oxidative Stress Markers, and Adipocytokines will be conducted pre and post-intervention.
Status | Not yet recruiting |
Enrollment | 72 |
Est. completion date | October 2024 |
Est. primary completion date | September 2024 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 20 Years to 50 Years |
Eligibility | Inclusion Criteria: - Residents of UAE, both males and females - Ages 20-50 years - Uncomplicated Type 2 Diabetic on meds, - Normal lean BMI - Overweight and Obese Exclusion Criteria: - Recent orthopedic surgery in the LLs - Pain in the LLs starting from Hips to Ankle. - Presence of Varicose Veins in the LLs - Present History of any cardiovascular condition - Pregnant females - Morbid Obesity - Diabetics undergoing Insulin therapy only - Smokers and alcohol consumption |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
University of Sharjah |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | BMI | kg/m2 | 3 months | |
Other | Anthropometric data including weight, height and fat percentage | Measured in kgs, cms and % respectively | 3 months | |
Other | Physical Activity and Food habits | Questionnaire (International Physical Activity Questionnaire and Food Frequency Questionnaire) | 3 months | |
Other | Venous blood specimens | Measured in mL, using blood test by specialized personnel | 3 months | |
Primary | Adipocytokine levels in the blood | Measured in µg/ml, using blood test by specialized personnel | 3 months | |
Secondary | Soleus Muscle endurance through Heel Raise Test. • Inflammatory and Oxidative Stress markers through blood sample. | Measured as a number, in repetitions. Detailed procedure described previously. | 3 months |
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