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NCT05110846 Clinical Trial

A Study of CT-868 in Overweight and Obese Participants With Type 2 Diabetes Mellitus

Obesity Clinical Trial

Official title:
A Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Multiple-Center Study to Evaluate the Efficacy, Safety, and Tolerability of CT-868 Administered for 26 Weeks to Overweight and Obese Participants With Type 2 Diabetes Mellitus

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT05110846
Other study ID # CT-868-002
Secondary ID
Status Active, not recruiting
Phase Phase 2
First received
Last updated
Start date February 22, 2022
Est. completion date March 2023

Study information
Verified date February 2022
Source Carmot Therapeutics, Inc.
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

A Study to Assess the effect of CT-868 in hemoglobin A1c (HbA1c) in Overweight and Obese Participants with Type 2 Diabetes Mellitus.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 96
Est. completion date March 2023
Est. primary completion date February 2023
Accepts healthy volunteers No
Gender All
Age group 18 Years to 75 Years
Eligibility Inclusion Criteria: - Males or Females with T2DM - BMI of =27 kg/m2, inclusive - 18-75 years old, inclusive - Stable body weight for 3 months Exclusion Criteria: - Significant medical history - Uncontrolled diabetes - History of malignancy

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Placebo
Placebo
• CT-868
CT-868

Locations
Country Name City State
Mexico Carmot Clinical Center MX04 Guadalajara Jalisco
Mexico Carmot Clinical Center MX05 Mérida Yucatan
Mexico Carmot Clinical Center MX03 Mexico City
Mexico Carmot Clinical Center MX01 Monterrey Nuevo Leon
Mexico Carmot Clinical Center MX02 Monterrey Nuevo Leon
United States Carmot Clinical Center US01 Los Angeles California

Sponsors (1)
Lead Sponsor Collaborator
Carmot Therapeutics, Inc.

Countries where clinical trial is conducted

United States,  Mexico, 

Outcome
Type Measure Description Time frame Safety issue
Primary Change in hemoglobin A1c (HbA1c) Baseline up to 12 and 26 weeks
Secondary Change in mean body weight Baseline up to 12 and 26 weeks
Secondary Fasting plasma glucose Baseline up to 12 and 26 weeks
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