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Biomarkers in Obese Patients With Knee Osteoarthritis; Weight Loss — BIO-LOSEIT-I  

Obesity Clinical Trial

Official title:
Biomarkers in Obese Patients With Knee Osteoarthritis Following a Significant Weight Loss

Clinical Trial Summary

This is a substudy to a randomised trial investigating the effect of liraglutide on body weight and pain in overweight or obese patients with knee osteoarthritis (NCT02905864).

This substudy aims to investigate any changes in biomarkers associated with the initial 8-week weight loss intervention

Clinical Trial Description

In the parent trial, patients will be subjected to an 8-week diet intervention phase including a low-calorie diet and dietetic counselling, after which they will be randomised to receive either liraglutide 3 mg or liraglutide 3 mg placebo as an add-on to dietetic guidance on re-introducing regular foods and a focus on continued motivation to engage in a healthy lifestyle. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02931344
Study type Interventional
Source Parker Research Institute
Contact
Status Active, not recruiting
Phase N/A
Start date November 2016
Completion date June 2019
View Details
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