Diabetes Nutrition Algorithm - Prediabetes — DiNA-P  

Obesity Clinical Trial

Official title: Diabetes Nutrition Algorithm - Prediabetes (Dietary Strategies in the Prevention of Diabetes Mellitus Type 2 in a High-risk Cohort)

Status Recruiting

Clinical Trial Summary

Prediabetes, defined by either impaired fasting glucose and/or impaired glucose tolerance, is a known high-risk condition predisposing to future diabetes mellitus type 2. Strategies to prevent progression from prediabetes to diabetes have been widely studied, however, without striking long-term effects of any kind of intervention (pharmacological, behavioral...). The investigators therefore investigate certain nutritional approaches concerning nutrient content and favorable food components, targeting metabolic improvement.

Clinical Trial Description

Prediabetes, defined by either impaired fasting glucose and/or impaired glucose tolerance, is a known high-risk condition predisposing to future diabetes mellitus type 2. Strategies to prevent progression from prediabetes to diabetes have been widely studied, however, without striking long-term effects of any kind of intervention (pharmacological, behavioral...). The investigators therefore investigate certain nutritional approaches concerning nutrient content and favorable food components, targeting metabolic improvement.

The main comparison will assess differences in metabolic outcome due to low-carb or low-fat dietary intervention in short- and long-term design.

Additionally, the role of PUFA will be assessed during long-term intervention to achieve better maintenance of metabolic improvements from the first study phase. ;

Related Conditions & MeSH terms

• Diabetes Mellitus
• Diabetes Mellitus Type 2
• Diabetes Mellitus, Type 2
• Dyslipidemias
• Dyslipoproteinemia
• Glucose Intolerance
• NAFLD
• Obesity
• Prediabetes
• Prediabetic State

• NCT number: NCT02609243
• Study type: Interventional
• Source: German Institute of Human Nutrition
• Contact: Stefan Kabisch, Dr. med.
• Phone: 030 450 514
• Email: stefan.kabisch@charite.de
• Status: Recruiting
• Phase: N/A
• Start date: July 2013
• Completion date: December 2021