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Kagoshima Collaborate Trial in Metabolic Syndrome (KACT Study) — KACT  

Obesity Clinical Trial

Official title:
Effects of Valsartan on Metabolic Syndrome in Patients With Hypertension

Clinical Trial Summary

The purpose of this study is to consider the following points in patients with hypertension who complicated by metabolic syndrome for Valsartan basis treatment and an existing, standard treatment.

- Blood pressure control

- Changing of adiponectin and plasminogen activator inhibitor-1

- Influence metabolizing and cardiac function, etc.

Clinical Trial Description

The primary endpoints are:

- blood pressure control

- Adiponectin and plasma type1 plasminogen active inhibitor

The secondary endpoints are

- HOMA-IR

- HbA1c

- TNF-α

- IL-6

- Plasma B-type natriuretic peptide

- LVMI

- E/A ratio

- Tei-index

- Apo-J ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00790946
Study type Interventional
Source Kagoshima University
Contact Chuwa Tei, MD, PhD
Email tei@m.kufm.kagoshima-u.ac.jp
Status Recruiting
Phase Phase 4
Start date June 2006
Completion date December 2009
View Details
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