Obesity Clinical Trial
To examine the effects of ethnicity, socioeconomic status (SES) and behavior in overweight adults.
BACKGROUND:
In 1999, more than 55 percent of United States adults were overweight, an increase of 8
percent in fifteen years. Because overweight is associated with cardiovascular disease (CVD)
morbidity and mortality, the alarming increase in overweight underscored the need for
innovative and effective weight-loss interventions. Tailored interventions specifically
designed for high-risk subgroups can compliment existing population-based approaches.
However, before designing such interventions, sociodemographic characteristics of those at
high risk must be identified.. Although past studies have shown that ethnicity is associated
with overweight, these studies suffered from potential confounding from SES because ethnic
minority groups are disproportionately poor. Past studies have been compromised by limited
sample size at the extremes of SES such as higher SES Mexican-Americans or Blacks, and/or
lower SES Whites.
Weight loss is affected by multiple perceptions and behaviors, such as perceptions of
overweight, physical activity, dietary habits, smoking, and alcohol use. Although past
epidemiological research has investigated the independent effects of such influences on
weight, research to date has not identified whether distinct clusters of weight perceptions
and behaviors exist among overweight adults. Given that such clusters may differ by
sociodemographic characteristics, identifying clusters may contribute to the design of
innovative and tailored weight-loss interventions that address the presence of multiple
influences on weight loss and increase the likelihood of successful interventions.
DESIGN NARRATIVE:
The study had four specific aims: (1) to identify subgroups at high risk of overweight based
on sociodemographic characteristics (e.g., ethnicity and SES): (2a) to determine whether
distinct clusters of weight perceptions and behaviors exist among overweight adults and (2b)
to determine whether the clusters differ by sociodemographic characteristics; (3) to
determine whether clusters in the overweight sample exist among normal-weight adults, and
(4) to propose tailored weight-loss interventions to be tested empirically in the future.
Data were analyzed, by gender, for 3203 Black, 2989 Mexican-American, and 3761 white men and
women, ages 25-64, who participated in the third National Health and Nutrition Examination
Survey (NHANES III), 1988-1994). This national survey of the United States population
over-sampled by the two largest ethnic minorities, Blacks and Mexican-Americans, and
provided sufficient sample sizes at the extremes of SES.
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