Obesity Clinical Trial
Official title:
Hepatic Fat Content and Mitochondrial Flux in Obese Youth Before and After Bariatric Surgery
Assess the impact of bariatric surgery on hepatic energy metabolism and glucose and insulin dynamics in obese youth
A metabolic study that will be performed prior to and 12 months following bariatric surgery. The study will include 31-phosphorus magnetic resonance spectroscopy to measure phosphate concentrations in the liver; a 4 hour mixed meal tolerance test, an intravenous arginine test, Abdominal Magnetic Resonance Imaging (MRI) for visceral and hepatic fat, Magnetic Resonance (MR) Elastography of the liver, indirect calorimetry, body composition assessment with Bodpod, serum metabolomics and hepatic tissue mitochondrial measures from the time of surgery only. ;
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