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Clinical Trial Summary

Lithium therapy is cornerstone in therapy of bipolar disorders. A well known side-effect of lithium therapy is a urinary concentration defect which manifests in it's most severe form as nephrogenic diabetes insipidus. The development of urinary concentration defects and its progression to nephrogenic diabetes insipidus in the population of lithium treated patients is unknown and therefore this study aims to evaluate the decline of urinary concentration defects in a Dutch population of lithium treated patients. In this prospective cohort study, 51 participants treated with lithium at Canisius Wilhelmina Hospital, Nijmegen and included in the previous study in 2012 will be approached to undergo a follow-up dDAVP-test.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05307042
Study type Observational
Source Radboud University Medical Center
Contact M.J. van der Aa
Phone (073) 553 30 71
Email merel.vanderaa@radboudumc.nl
Status Not yet recruiting
Phase
Start date May 2022
Completion date December 2022

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