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Neoplasm Metastasis clinical trials

View clinical trials related to Neoplasm Metastasis.

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NCT ID: NCT00184288 Withdrawn - Melanoma Clinical Trials

Proton MR Spectroscopy of Brain Metastases in Evaluation of Treatment Response.

Start date: November 2004
Phase: N/A
Study type: Observational

The aim of the study is to investigate the feasibility of in vivo single volume MR spectroscopy in evaluation of treatment response in patients with brain metastases, using 3T MR instrument. In order to optimize and avoid ineffective treatment of patients with brain metastases, in vivo MR spectroscopy can be an useful tool.

NCT ID: NCT00184275 Completed - Melanoma Clinical Trials

Characterization of Brain Metastases

Start date: May 2005
Phase: N/A
Study type: Observational

The purpose is to characterize tumour biological markers in brain metastases tissue from patients with different primary tumour by using ex vivo techniques as high-resolution magic angle spinning MR spectroscopy and micro array.

NCT ID: NCT00182754 Completed - Clinical trials for Unspecified Adult Solid Tumor, Protocol Specific

Octreotide in Treating Patients With Cancer-Related Malignant Ascites

Start date: October 2005
Phase: Phase 3
Study type: Interventional

RATIONALE: Octreotide may be an effective treatment for malignant ascites. It is not yet known whether octreotide is more effective than a placebo in treating malignant ascites. PURPOSE: This randomized phase III trial is studying octreotide to see how well it works compared to placebo in treating patients with cancer-related malignant ascites.

NCT ID: NCT00181558 Completed - Prostate Cancer Clinical Trials

Atrasentan and Zometa for Men With Prostate Cancer Metastatic to Bone

Start date: December 2001
Phase: Phase 2
Study type: Interventional

The main purpose of this study is to look at the effects (good or bad) that Atrasentan given alone and Atrasentan given with Zometa has on levels of bone formation and bone destruction in men with prostate cancer that has spread to the bones.

NCT ID: NCT00178243 Completed - Neoplasm Metastasis Clinical Trials

Feasibility of Treatment of Cancer Involving the Liver With High Dose Radiation

Start date: n/a
Phase: Phase 1/Phase 2
Study type: Interventional

A study is being conducted by the University of Rochester Cancer Center (URCC) in which patients with liver cancer will be treated with high dose conformal radiation therapy. This type of radiation uses new techniques which aim the radiation to the sites of disease allowing the tumor to receive a high dose and the surrounding normal liver tissue to receive a low enough dose that the normal tissue should remain free from injury. The purpose of the study is to determine if the conformal radiation therapy is safe, tolerable and effective in treating liver cancer and to determine the side effects caused by this treatment. A second objective is to determine if the levels of a special type of protein (called cytokines) found in the blood are related to this treatment.

NCT ID: NCT00174096 Recruiting - Metastasis Clinical Trials

The Role of Stromal Cell-Derived Factor-1 (SDF-1)/CXC Chemokine Receptor 4 (CXCR4) in Metastasis of Laryngeal and Hypopharyngeal Squamous Cell Carcinoma

Start date: August 2005
Phase: N/A
Study type: Observational

The purpose of this study is to investigate the relationship between SDF-1/CXCR4 and metastasis of laryngeal and hypopharyngeal squamous cell carcinomas.

NCT ID: NCT00172003 Completed - Neoplasm Metastasis Clinical Trials

Effect of Zoledronic Acid in Patients With Renal Cell Cancer and Bone Metastasis

Start date: September 2004
Phase: Phase 4
Study type: Interventional

It is the aim of this clinical study to evaluate the skeletal-related event rate under therapy with zoledronic acid in patients with renal cell cancer having at least one cancer-related bone lesion.

NCT ID: NCT00171964 Completed - Pain Clinical Trials

Efficacy and Tolerability of Zoledronic Acid With Radiotherapy in Pts With Advanced Osteolytic Bone Lesions

Start date: May 2002
Phase: Phase 4
Study type: Interventional

It is the aim of this multicentric clinical study to assess the efficacy and tolerability of zoledronic acid in combination with radiotherapy in patients with advanced osteolytic bone lesions in terms of the reduction of pain and analgesic consumption.

NCT ID: NCT00171873 Completed - Clinical trials for Neuroendocrine Tumors

Antiproliferative Effect of Octreotide in Patients With Metastasized Neuroendocrine Tumors of the Midgut

Start date: September 2001
Phase: Phase 3
Study type: Interventional

Placebo-controlled prospective randomized phase III study to investigate the antiproliferative effect of octreotide in patients with metastasized neuroendocrine tumors of the midgut

NCT ID: NCT00171587 Completed - Neoplasm Metastasis Clinical Trials

Study of the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Effects of Vatalanib in Combination With Capecitabine in Patients With Advanced Cancer

Start date: May 2002
Phase: Phase 1/Phase 2
Study type: Interventional

The objective of this study is to assess the safety, tolerability, dose limiting toxicity, and maximum tolerated dose of vatalanib administered orally once daily in combination with capecitabine in patients with advanced cancer. The study is also designed to determine the effect of vatalanib on the pharmacokinetics of capecitabine and the effect of capecitabine on the pharmacokinetics of vatalanib, and to describe the anti-tumor activity of this combination regimen.