Gene Therapy for the Treatment of Chronic Stable Angina

Status Withdrawn

Clinical Trial Summary

The purpose of this study is to evaluate the safety and tolerability of catheter based injections of VM202 into the heart.

Clinical Trial Description

A phase I/II, open label, dose-escalation, multicenter, 12 month study designed to assess the safety and tolerability of catheter based percutaneous myocardial injection of VM202 in patients with chronic refractory myocardial ischemia. The study will consist of three (3) cohorts with a total of 4 subjects enrolled in each cohort. Endocardial injections will be performed with the MyoStar Injection Catheter under guidance of the NOGA XP Cardiac Navigation System. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01002495
Study type	Interventional
Source	Helixmith Co., Ltd.
Contact
Status	Withdrawn
Phase	Phase 1/Phase 2
Start date	March 2015
Completion date	January 2016

View Details

See also
Status	Clinical Trial	Phase
Not yet recruiting	`NCT06032572` - Evaluation of the Safety and Effectiveness of the VRS100 System in PCI (ESSENCE)	N/A
Recruiting	`NCT05846893` - Drug-Coated Balloon vs. Drug-Eluting Stent for Clinical Outcomes in Patients With Large Coronary Artery Disease	N/A
Completed	`NCT04153006` - Comparison of Fingerstick Versus Venous Sample for Troponin I.
Completed	`NCT01205776` - EXCEL Clinical Trial	N/A
Active, not recruiting	`NCT04555174` - BIOFLOW-VIII All-comers Orsiro Mission Safety and Performance Registry
Recruiting	`NCT04582877` - Pressure Guidewire System Multi-center, Prospective, Self-Control, Clinical Trial	N/A
Recruiting	`NCT04390672` - Multivessel TALENT	N/A
Recruiting	`NCT03265535` - Validation of a Single Rest-Stress Imaging Protocol for Myocardial Perfusion Imaging
Not yet recruiting	`NCT04522583` - Increased CRP Concentrations in Patients Admitted to the Emergency Department With Troponin Elevation Aids to Rule Out Coronary Ischemia
Completed	`NCT02510547` - Comparison of a CrossBoss First Versus Standard Wire Escalation Strategy for Crossing Coronary Chronic Total Occlusion: the "CrossBoss First" Trial	Phase 4
Terminated	`NCT02407626` - Optimization of Cardioprotection in Diabetic Patients Undergoing Cardiac Surgery	N/A
Completed	`NCT02554006` - Predischarge Bundle to Minimize Negative Impact on Quality of Life of Nuisance Bleedings	N/A
Active, not recruiting	`NCT02189499` - Feasibility Study of the Amaranth Medical FORTITUDE Bioresorbable Drug-Eluting Coronary Stent	Phase 2
Completed	`NCT02197065` - Pilot Study of Atorvastatin for Orthopedic Surgery Patients	Phase 2
Completed	`NCT02264717` - Dan-NICAD - Danish Study of Non-Invasive Diagnostic Testing in Coronary Artery Disease	N/A
Recruiting	`NCT01681381` - Evaluate Safety And Effectiveness Of The Tivoli® DES and The Firebird2® DES For Treatment Coronary Revascularization	N/A
Completed	`NCT01655043` - Absolute Quantification of Coronary Flow Reserve by Stress Perfusion MRI	Phase 2
Terminated	`NCT01892917` - BIOFLOW-III Hungary Satellite Registry	N/A
Completed	`NCT01679886` - Comparison of Rubidium PET and SPECT With CZT Crystals for Detection of Myocardial Ischemia in Overweighed Patients and Women	N/A
Completed	`NCT02707445` - Genotyping Influences Outcome of Coronary Artery Stenting	N/A