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Clinical Trial Summary

Around 10% of patients with myocardial infarction (MI) present with nonobstructive coronary arteries (MINOCA) which pathophysiology is often uncertain. The aim of the study is to evaluate inflammation and endothelial dysfunction biomarkers in MINOCA patients during both acute and stable phases, comparing them with those with MI and obstructive coronary arteries (MICAD).


Clinical Trial Description

Prospective observational study in patients with Myocardial Infarction (MI) divided into two groups: MI with obstructive coronary arteries (MICAD) and MI with non-obstructive coronary arteries (MINOCA). Levels of interleukin-6, tumor necrosis factor-alpha, high-sensitivity C- reactive protein, and asymmetric dimethylarginine will be determined at three time points: within the 24 hours from the onset of pain, discharge, and two months after MI. The association of biomarkers, normalized by peak troponin value, with the risk of MINOCA will be evaluated using logistic regression. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06446895
Study type Observational
Source Hospital Universitario Getafe
Contact MARIA JESUS ESPINOSA, MD
Phone 636581691
Email mariajesusespinosapascual@gmail.com
Status Recruiting
Phase
Start date October 1, 2020
Completion date May 31, 2025

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