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Clinical Trial Summary

A Phase I Pharmacologic Study of CYC140, a polo-like kinase 1 inhibitor, in Patients with Advanced Leukemias or Myelodysplastic Syndromes


Clinical Trial Description

This is a First in Human, open-label, single arm, dose escalation study in patients with advanced leukemias or myelodysplastic syndromes. Patients will receive CYC140 as a 1 hr infusion once a week for 2 weeks followed by 1 week of rest on an outpatient basis. One treatment cycle is 3 weeks. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03884829
Study type Interventional
Source Cyclacel Pharmaceuticals, Inc.
Contact Mark Kirschbaum, MD
Phone 6263163394
Email mkirschbaum@cyclacel.com
Status Recruiting
Phase Phase 1
Start date March 25, 2019
Completion date September 2023

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