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Mouth Diseases clinical trials

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NCT ID: NCT06381700 Not yet recruiting - Oral Disease Clinical Trials

Effectiveness of MySmile App for Improving the Oral Health of Secondary School Children:

Start date: May 2024
Phase: N/A
Study type: Interventional

The goal of this cluster-randomised control trial is to assess the effectiveness of the MySmile app for improving oral health in secondary school children. The main questions it aims to answer are: 1. Will the MySmile app be more effective in improving secondary school children's dental plaque and gingival health over and above the existing school dental service (SDS)? 2. Will the MySmile app be more effective in improving secondary school children's oral health knowledge, attitudes, and behaviours over and above the existing SDS? 3. Is the MySmile app easy to use by secondary school children? 4. Is the MySmile app acceptable to use from the perspective of secondary school children? Participants in the intervention group will receive the SDS and MySmile app. The control group will receive SDS only. Therefore the researcher will compare between the intervention and control group in terms of dental plaque, gingival health, oral health knowledge, oral health attitudes and oral health behaviours.

NCT ID: NCT06381505 Not yet recruiting - Oral Cavity Disease Clinical Trials

RetracTOR/ Retractor for Image Guided Trans-Oral Surgery

Start date: May 15, 2024
Phase:
Study type: Observational

This study aims to demonstrate that a polymer retractor functions the same as a standard metal retractor used during endoscopy and throat surgery. The retractor is the device that holds the mouth open so the surgeon can easily access the mouth and throat. For example, this study aims to confirm that the mouth is held open the same amount with a polymer retractor as it is with a metal retractor. Benchtop experiments have demonstrated that the metal and polymer retractor's function the same, and thus this study will use this in patients.

NCT ID: NCT06341959 Not yet recruiting - Oral Disease Clinical Trials

Can a Low-threshold Check-up Motivate Older People to Schedule a Dental Visit?

Start date: May 1, 2024
Phase: N/A
Study type: Interventional

There is little research on the effect of oral screening campaigns for improving oral health in older people. Therefore, the aim of this study is to investigate the effect of a low-threshold contact with an oral health professional, including an oral health examination, on dental attendance of older people (65 years of age or older).

NCT ID: NCT06251219 Not yet recruiting - Clinical trials for Hand, Foot and Mouth Disease

Active Case Finding of Clinical Hand Foot Mouth Disease in Children Aged 6 Months Old to 18 Years Old in Indonesia

Start date: February 1, 2024
Phase:
Study type: Observational

An observational study of active case surveillance to identify the pathogens of clinically diagnosed HFMD cases aged 6 months to 18 years old recruited from puskesmas and hospitals in Indonesia.

NCT ID: NCT06081868 Not yet recruiting - Dental Caries Clinical Trials

RCT on Effectiveness of Oral Health Preventive Programmes in School Children in Uganda

Start date: September 1, 2024
Phase: N/A
Study type: Interventional

Dental caries represents a challenge for Oral Health Services in several African Countries, like Uganda. Few studies have been reported the burden of oral health, its prevention and non-operative treatment among school children in African countries. Aim: To assess the prevalence and risk factors of dental caries and the effectiveness of strategies to prevent and treat dental caries using a non-operative approach among children in Gulu Municipality, Uganda. Methods: The proposal RCT is structured in three phases: 1. A descriptive cross-sectional survey to collect oral data among 610 school children selected using a multistage cluster sampling; 2. A randomized unblinded two-arm trial to assess the difference in the treatment/prevention of dental caries using non-operative means among school children in the Ugandian Gulu municipality; and 3. A comparison of oral health conditions between a group of children who will be given dental cleaning tools and followed up over time versus a control group. The oral health status of the participants will be assessed according to WHO and ICDAS guidelines. Stata 14.0. will be used for analysis; descriptive statistics will be carried out to analyze continuous and categorical variables and chi-square test as well as independent tests for bivariate analysis and modified poisson regression. In addition, the factors associated with dental caries will be determined by linear regression models using a statistical significance level of 5% (α = 0.05). Discussion: This trial will be the first trial conducted in Uganda assessing a school-based caries prevention programme using the WHO and ICDAS standardized international guidelines. The findings obtained will increase knowledge on oral health in Uganda school children and the effectiveness of community-based caries prevention programme in this population.

NCT ID: NCT06046768 Not yet recruiting - Oral Disorder Clinical Trials

Assessment and Remediation of Oral Disorders

ERTO
Start date: October 1, 2023
Phase: N/A
Study type: Interventional

As part of the Reference Center for Rare Diseases of the Robert Debré Hospital, many children have eating and verbal oral disorders. In this doctoral research, we question the psychological impact of oral disorders on the dynamics of family functioning.Our research entitled: Evaluation and Remediation of Orality Disorders (ERTO) aims to evaluate the impact of psychological care of the child and a support program for parents. We hypothesized that this comprehensive management could contribute to improving disorders and consequently modify parental representations of the child and his disorders. In addition, care focused on intra-family relations and communication would allow a decentralization and a repositioning of the problem of disorders within the family dynamic. The results of this research will have concrete applications for the management of children suffering from oral disorders.

NCT ID: NCT06040164 Not yet recruiting - Obesity Clinical Trials

Oral Endocannabinoids in People With Prediabetes and Diabetes

SMILE
Start date: October 1, 2023
Phase:
Study type: Observational

This study evaluates the relationship of endocannabinoids in saliva with inflammation and oral dysbacteriosis present in people with periodontal disease and prediabetes/type 2 diabetes

NCT ID: NCT05923762 Not yet recruiting - Oral Disease Clinical Trials

Oral Health Related Quality of Life

Start date: January 15, 2024
Phase:
Study type: Observational

As oral health has a major impact on general health and quality of life, good oral health are essential. The aspects of oral health that are most important for each individual vary, and quality of life is subjective, and influenced by the person´s experiences, perceptions, expectations and ability to adapt to circumstances. FDI World Dental federations definition of oral health is; "Oral health is multifaceted and includes the ability to speak, smile, smell, taste, touch, chew, swallow, and convey a range of emotions through facial expressions with confidence and without pain, discomfort, and disease of the craniofacial complex.

NCT ID: NCT05397587 Not yet recruiting - Clinical trials for Hand, Foot and Mouth Disease

An Immunity Persistence Study of Enterovirus 71 Inactivated Vaccine (Vero Cell)

Start date: July 30, 2022
Phase: Phase 4
Study type: Interventional

This is an open,observational and follow-up clinical trial based on the clinical trial of EV71 vaccine extended age group.The purpose of this study is to evaluate the immunity persistence of EV71 vaccine developed by Sinovac Biotech Co., Ltd in subjects aged 6 ~71 months after full immunization of two doses of vaccine.

NCT ID: NCT04637919 Not yet recruiting - Clinical trials for Hand, Foot and Mouth Disease

Safety and Immunogenicity of High-dose IN-B001 in Healthy Subjects

Start date: December 2020
Phase: Phase 1
Study type: Interventional

This study aims to evaluate the safety and immunogenicity of high-dose IN-B001 after administration in healthy subjects