Use of Cyclosporin A for the Treatment of Recurrent Miscarriage

Status Not yet recruiting

Clinical Trial Summary

The purpose of this study is to determine whether Cyclosporin A (CsA) - an immunosuppressant drug - in early pregnancy will reduce the risk of miscarriage in women who had a history of unexplained recurrent miscarriages, as compared with that treated with Dydrogesterone-an active comparator. The hypothesis is based on the evidence found in vitro and in vivo experiments that CsA can induce maternal-fetal tolerance so that it may reduce the risk of miscarriage.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02706470
Study type	Interventional
Source	Fudan University
Contact	Jiangfeng Ye, MD
Phone	86-21-33189900
Email	jiangfeng_ye@hotmail.com
Status	Not yet recruiting
Phase	Phase 2/Phase 3
Start date	May 2016
Completion date	December 2018

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