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NCT03190772 Clinical Trial

The Role of Expectations in the Pharmacological Treatment of Depression - An Experimental Investigation

Major Depressive Episode Clinical Trial

Official title:
The Role of Expectations in the Pharmacological Treatment of Depression - An Experimental Investigation

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03190772
Other study ID # 2017-12k
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date November 1, 2017
Est. completion date September 30, 2018

Study information
Verified date November 2018
Source Philipps University Marburg Medical Center
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The study aimes at identifying whether positive expectations have an impact on the way depressive participants experience emotions in the form of sadness.

Recruitment information / eligibility
Status Completed
Enrollment 94
Est. completion date September 30, 2018
Est. primary completion date September 30, 2018
Accepts healthy volunteers No
Gender Female
Age group 18 Years to 65 Years
Eligibility Inclusion Criteria:

- major depression (mild to moderate)

- fluent in German language

Exclusion Criteria:

- bipolar disorder, psychotic disorder, substance dependence

- cardiovascular disease, severe kidney or liver disease, epilepsy

- change of psychotropic medication intake within the last four weeks

- allergic to capsaicin

- allergic to sesame oil

- students in medicine, pharmacy, or psychology in their third year or older

- completed studies in medicine, pharmacy or psychology

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• Placebo nasal spray
The placebo nasal spray consists of sesame oil and does not contain any active drug.
• Film sequence
All groups watch the film sequence that is supposed to induce sadness.

Locations
Country Name City State
Germany Justus Liebig University Gießen Gießen Hessen
Germany Philipps University Marburg Marburg Hessen

Sponsors (1)
Lead Sponsor Collaborator
Philipps University Marburg Medical Center

Country where clinical trial is conducted

Germany, 

Outcome
Type Measure Description Time frame Safety issue
Primary Sadness Items of PANAS-X Directly after watching the film sequence, no follow-up assessments
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