Improving Depression Care for Elders: Coordinating Center

Major Depression Clinical Trial

— IMPACT  

Official title:

This Was a Five-year Seven-site Trial to Study the Cost-effectiveness of a Population Based Disease Management Program for Late Life Depression in Primary Care.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01561105
• Other study ID #: JAHF 98297
• Status: Completed
• Phase: N/A
• First received: March 20, 2012
• Last updated: March 26, 2012
• Start date: January 1999
• Est. completion date: June 2004

Study information

• Verified date: March 2012
• Source: University of California, Los Angeles
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Interventional

Clinical Trial Summary

Purpose: To determine the effectiveness of the Improving Mood-Promoting Access to Collaborative Treatment(IMPACT) collaborative care management program for late-life depression.

Description:

This study tested an organized method of delivering care for late life depression in primary care. Specifically, the investigators evaluated the effectiveness of this intervention as compared to 'care as usual'. The investigators studied the effect of the intervention on clinical outcomes such as depressive symptoms, functional status, health related quality of life. They also determined the cost-effectiveness of the intervention compared to care as usual.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 1801
• Est. completion date: June 2004
• Est. primary completion date: June 2004
• Gender: Both
• Age group: 60 Years and older

Eligibility

Inclusion Criteria:

• Major depression or dysthymia as diagnosed by a structured diagnostic interview.

• Patient plans to receive primary care at the study clinic for the next year.

Exclusion Criteria:

• Age under 60.

• Current symptoms or history of psychosis or mania as determined by structured diagnostic interview.

• Cognitive impairment as defined by a score less than 23 on a Mini Mental Status Examination.

• Terminal illness - defined as having a life expectancy of less than 6 months.

• Active alcohol abuse as determined by a screening interview.

• High suicide risk as determined by current plan for suicide or a history of more than 3 prior suicide attempts in the past 10 years.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Both Major Depression and Dysthymic Disorder
• Depression
• Depressive Disorder
• Depressive Disorder, Major
• Disease
• Dysthymic Disorder
• Major Depression

Intervention

Other:
• IMPACT
IMPACT is a collaborative care management program for late-life depression

Locations

Country	Name	City	State
n/a

Sponsors (5)

Lead Sponsor	Collaborator
University of California, Los Angeles	California HealthCare Foundation, Hogg Foundation, Robert Wood Johnson Foundation, The John A. Hartford Foundation

References & Publications (1)

Unützer J, Katon W, Callahan CM, Williams JW Jr, Hunkeler E, Harpole L, Hoffing M, Della Penna RD, Noël PH, Lin EH, Areán PA, Hegel MT, Tang L, Belin TR, Oishi S, Langston C; IMPACT Investigators. Improving Mood-Promoting Access to Collaborative Treatment — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Severity of depression symptoms	Severity measured by the 21-item Hopkins Symptom Checklist.		No
Secondary	Functioning	measured by the Sheehan Health-Related Functioning Index		No