Clinical Trials Logo

Macular Edema clinical trials

View clinical trials related to Macular Edema.

Filter by:

NCT ID: NCT02614937 Completed - Macular Edema Clinical Trials

Study of Squalamine Lactate for the Treatment of Macular Edema Related to Retinal Vein Occlusion

Start date: April 2013
Phase: Phase 1/Phase 2
Study type: Interventional

This was a prospective, single center, open label, randomized study evaluating the biological effect of squalamine lactate ophthalmic solution, 0.2% combined with intravitreous ranibizumab in patients with macular edema secondary to branch, hemi-central and central retinal vein occlusion (BRVO, HRVO, CRVO).

NCT ID: NCT02614625 Recruiting - Diabetes Clinical Trials

Spectral-domain Optical Coherence Tomography of the Eye

Start date: December 2014
Phase: N/A
Study type: Observational

An increasing number of clinical studies on SD-OCT of ocular pathologies and potential new clinical applications has recently been published in the peer-reviewed literature. However, the successful use of SD-OCT in routine clinical use depends upon the diagnostic sensitivity, biometric accuracy and reliability of the SD-OCT machines. This prospective, comparative, observational study aims to evaluate the imaging quality and diagnostic performance of two commercially available SD-OCT machines for both the anterior and posterior segment of the eye.

NCT ID: NCT02609165 Completed - Clinical trials for Retinitis Pigmentosa

Nerve Growth Factor Eye Drops Treatment in Patients With Retinitis Pigmentosa and Cystoid Macular Edema

NEMO
Start date: May 2015
Phase: Phase 2
Study type: Interventional

This study aims at investigating the therapeutic potential of recombinant human Nerve Growth Factor ( rhNGF ) eye drops treatment in patients with Retinitis Pigmentosa (RP) associated with cystoid macular edema (CME) in a phase II, randomized, double-masked, controlled clinical trial.

NCT ID: NCT02598869 Withdrawn - Uveitis Clinical Trials

Posterior Subtenon Versus Intravitreal Injection of Triamcinolone Acetonide for Treatment of Uveitic Cystoid Macular Edema

Start date: November 30, 2015
Phase: Phase 4
Study type: Interventional

Macular edema is the most common sight threatening complication of uveitis which can lead to permanent loss of central vision. Triamcinolone acetonide ( the study drug)injection for treatment of cystoid macular edema(CME) is well established. The purpose of this study is to compare the safety and efficacy of injecting the study drug inside the eye(intravitreal injection) and behind the eye(subtenon injection)

NCT ID: NCT02595398 Completed - Uveitis Clinical Trials

Suprachoroidal Injection of CLS-TA in Subjects With Macular Edema Associated With Non-infectious Uveitis

PEACHTREE
Start date: November 17, 2015
Phase: Phase 3
Study type: Interventional

The study is designed to evaluate the safety and efficacy of suprachoroidally administered triamcinolone acetonide, CLS-TA, in subjects with macular edema associated with non-infectious uveitis.

NCT ID: NCT02585401 Completed - Clinical trials for Age-related Macular Degeneration (AMD)

Evaluation of Physician Knowledge of Safety and Safe Use Information for Aflibercept in Canada

Start date: February 18, 2016
Phase: N/A
Study type: Observational

The primary objective of this study is to measure physician knowledge and understanding of the key safety information contained in the Eylea vial preparation instruction card, the intravitreal injection procedure video, and the product monograph.

NCT ID: NCT02581995 Completed - Macular Edema Clinical Trials

Investigation of the Change of Vision-related Quality of Life in Subjects Treated With Aflibercept According to EU Label for DME.

AQUA
Start date: November 19, 2015
Phase: Phase 4
Study type: Interventional

To evaluate the change in quality of life (NEI VFQ 25) in subjects with DME during the first year of treatment with aflibercept according to the EU Label.

NCT ID: NCT02571972 Completed - Clinical trials for Diabetic Macular Edema

Dorzolamide-timolol Drops With Injections to Treat AMD, RVO or DME.

Start date: February 1, 2015
Phase: Phase 2
Study type: Interventional

This study seeks to evaluate the effect of topical aqueous suppression on the anatomic and functional response to intravitreal anti-vascular endothelial growth factor (VEGF) injections in non-responders with wet age-related macular degeneration.

NCT ID: NCT02559180 Completed - Clinical trials for Diabetic Retinopathy

Treatment of Diabetic Macular Edema With Aflibercept in Subjects Previously Treated With Ranibizumab or Bevacizumab

SwapTwo
Start date: October 2015
Phase: Phase 4
Study type: Interventional

Treatment of diabetic macular edema with intravitreal aflibercept in subjects previously treated with intravitreal anti-Vascular endothelial growth factor (VEGF) agents (ranibizumab or bevacizumab)

NCT ID: NCT02556723 Completed - Clinical trials for Diabetic Macular Edema

Intravitreal Injections of Ziv-aflibercept for Macular Diseases

Start date: September 2014
Phase: N/A
Study type: Interventional

Diabetic macular edema (DME), wet-AMD and macular edema secondary to vein occlusions are the leading cause of blindness in developed countries. Several therapies have been studied as such laser treatment and intravitreal injections of corticosteroids or anti-VEGF drugs. In terms of public health the long term treatment with the current available drugs is very expensive and new therapies with the same or better effect should be investigated. This study intends to evaluate the efficacy and safety of intravitreal injections of ziv-aflibercept for the treatment of patients with DME, wet-AMD and macular edema secondary to vein occlusions.