Asthma Clinical Trial
Official title:
Center for Reducing Asthma Disparities - Northwestern University/Cook County Hospital Centers
The purpose of this study is to characterize the relationship of social stress, coping, and self-regulatory health behaviors in the context of asthma disparities among African American and low income populations.
BACKGROUND:
Asthma is a serious chronic condition affecting over 14 million Americans, but the
prevalence rates are higher in certain populations (e.g. 10% in inner-cities and 30% among
the homeless versus 5% in a general population of whites). African Americans and Hispanics
from the Northeast are twice as likely to die from asthma as whites. African Americans are
four times as likely to be hospitalized for asthma and are five times more likely than
whites to seek care for asthma at an emergency department. Reasons for these higher rates
are not certain, and most likely result from an interaction of risk factors, such as
environmental exposures, genetic predisposition, access to appropriate medical care,
socioeconomic status, and cultural health practices. The National Heart, Lung, and Blood
Institute supports a variety of activities to address the pressing public health problems
posed by asthma. However, progress in reducing disparities has been disappointingly slow.
Separate, independent research projects have generated important clues for understanding the
nature and scope of the problem. A more coordinated, interdisciplinary and comprehensive
approach to research is needed to take advantage of these clues, move the science further
and faster, and increase our capacity to improve health outcomes among minority and
economically disadvantaged populations. Cooperative centers of research that foster
partnerships among minority medical centers, research intensive institutions, and the
communities in which asthma patients live will promote such advancement.
The Request for Applications for the Centers for Reducing Asthma Disparities was released in
October 2001. The objective of the program is to promote partnerships (called centers)
between a minority serving institution (MSI) that may not have a strong research program and
a research intensive institution (RII) that has a track record of NIH-supported research and
patient care. The purpose of the partnership is to conduct collaborative research on asthma
disparities (i.e., greater prevalence of asthma, higher rates of morbidity due to asthma,
and lesser access or use of quality medical care among minorities and poor).
DESIGN NARRATIVE:
The project will develop a collaborative research program between Northwestern University
Feinberg School of Medicine and Cook County Hospital to fully characterize the relationship
of social stress, coping, and self-regulatory health behaviors in the context of asthma
disparities among African American and low income populations. Once characterized, the
project will then develop and test an intervention strategy to reduce asthma disparities in
high-risk populations based on evidence-based models that have demonstrated success in
social work, nursing, and community interventions.
There are four research aims for the center: (1) To develop and validate culturally
appropriate psychosocial instruments related to the underlying causes of disparity in asthma
morbidity; (2) To identify the structural relationships of psychosocial factors to other
known influential factors related to disparities in asthma outcomes; (3) To study the
changes in structural relationship among influential factors in asthma disparity over time,
as related to changes in health status; (4) To develop, pilot test, and field test a
community-based asthma team (peer coach, asthma nurse, and social worker) intervention to
enhance individuals ability to cope with chronic illness and improve asthma-related
behaviors. A second major goal of the Center will be to train and mentor new clinical
investigators and social scientists to be able to conduct research in this field of
interest.
The study completion date listed in this record was obtained from the "Project End Date"
entered in the Query View Report (QRV) record.
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Primary Purpose: Treatment
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