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Lung Diseases, Obstructive clinical trials

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NCT ID: NCT00935181 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Respiratory Muscle Stretching in Chronic Obstructive Pulmonary Disease (COPD)

Start date: January 2006
Phase: Phase 4
Study type: Interventional

Objective: The investigators studied the effects of respiratory muscle stretching in an 8-week pulmonary rehabilitation program. Methods: This was a simple-blind parallel controlled trial, conducted an out-patient clinic. Twenty six patients with COPD (mean age 68 ± 6 y, percent of predicted FEV1 47 ± 16) were randomized to either respiratory muscle stretching group plus exercise training (RMS), and exercise training group (Sham), in an 8-week exercise program that had 3 sessions per week. The investigators measured inspiratory and expiratory muscle strength (by maximal inspiratory and expiratory pressure - PIM and PEM), exercise capacity (by 6-minute walk distance), dyspnea and quality of life.

NCT ID: NCT00934713 Completed - Clinical trials for Signs and Symptoms, Respiratory

The Effect of Montelukast Treatment in Wheezy Infants

Montelukast
Start date: September 2004
Phase: Phase 4
Study type: Interventional

The study is designed to evaluate the efficacy of montelukast on symptom-free days in unselected group of very young children with wheeze and recurrent asthma like symptoms. The secondary aim was to evaluate the effect of montelukast on lung function, airway responsiveness, airway inflammation and use of rescue medication.

NCT ID: NCT00932646 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Characterisation of 24-hour FEV1-time Profiles of Inhaled BI 1744 CL and Inhaled Foradil in Patients With Chronic Obstructive Pulmonary Disease

Start date: June 2009
Phase: Phase 3
Study type: Interventional

The study is intended to characterize the lung function profile of BI1744 in COPD patients where patients will perform pulmonary function tests at regular intervals for 24 hours at the end of a 6 week treatment period. Each patient will receive all four treatments.

NCT ID: NCT00931385 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Characterization of 24 Hour Spirometry Profiles of Inhaled BI 1744 CL and Inhaled Foradil in Patients With Chronic Obstructive Pulmonary Disease

Start date: June 2009
Phase: Phase 3
Study type: Interventional

The study is intended to characterize the lung function profile of BI1744 in COPD patients where patients will perform pulmonary function tests at regular intervals for 24 hours at the end of a 6 week treatment period. Each patient will receive all four treatments.

NCT ID: NCT00929734 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease (COPD)

Effect of Rosuvastatin Therapy in Patients With Stable Chronic Obstructive Pulmonary Disease

RODEO
Start date: March 2010
Phase: Phase 2
Study type: Interventional

The purpose of this study is to investigate whether rosuvastatin improves measures of endothelial function, decreases measures of inflammation, and improves pulmonary function in patients with stable chronic obstructive pulmonary disease.

NCT ID: NCT00929110 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

1-year Study to Assess the Efficacy, Safety, and Tolerability of Glycopyrronium Bromide (NVA237) in Chronic Obstructive Pulmonary Disease (COPD)

GLOW2
Start date: June 2009
Phase: Phase 3
Study type: Interventional

This study was designed to investigate the 1 year efficacy and safety of the 50 µg once daily (od) dose of glycopyrronium bromide (NVA237) in patients with moderate to severe chronic obstructive pulmonary disease.

NCT ID: NCT00922051 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease (COPD)

Acute Effects of Acu-Transcutaneous Electrical Nerve Stimulation (Acu-TENS) on Forced Expiratory Flow Volume in One Second (FEV1) and Blood β-Endorphin Level in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Start date: March 2008
Phase: N/A
Study type: Interventional

The objective of this study is to investigate the effectiveness of Acu-TENS (transcutaneous electrical nerve stimulation applied on acupoints) on lung functions, dyspnoeic symptoms and its association with beta endorphin level in subjects with COPD.

NCT ID: NCT00917150 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

To Investigate the Efficacy and Safety of OPC-6535 in Chronic Obstructive Pulmonary Disease (COPD) Patients

Start date: March 2009
Phase: Phase 2
Study type: Interventional

To investigate the efficacy and safety of OPC-6535 in COPD patients, using the measurement of trough FEV1 over time as the primary endpoint.

NCT ID: NCT00914810 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease (COPD)

Effect of Supplemental Vitamin D on Skeletal Muscle Function in Chronic Obstructive Pulmonary Disease (COPD) Patients

Start date: June 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether or not vitamin D supplementation can improve physical performance in persons with severe chronic obstructive pulmonary disease (COPD).

NCT ID: NCT00909779 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Safety Study of Arformoterol Tartrate Inhalation Solution in Chronic Obstructive Pulmonary Disease (COPD) Subjects

Start date: June 2009
Phase: Phase 3
Study type: Interventional

This is a multi-center study to evaluate the long-term safety of arformoterol 15 mcg twice daily (BID) in the treatment of subjects with moderate-to-severe COPD. Study participation will consist of a total of 6 visits over approximately 1 year.