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Lidocaine clinical trials

View clinical trials related to Lidocaine.

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NCT ID: NCT06379490 Recruiting - Lidocaine Clinical Trials

Ultrasound-guided Infraclavicular Block With Lidocaine or Ropivacaine for Closed Reduction of Distal Radius Fractures

Start date: April 23, 2024
Phase: Phase 3
Study type: Interventional

To investigate the feasibility of the lateral infraclavicular plexus brachialis (LIC) block for acute closed reduction of distal radius fractures, the investigators will compare the pain-relieving and muscle-relaxing properties of the LIC block with short- and long-acting local anesthetics in different concentrations but at the same volume. In addition to motor and sensory blockade during repositioning, feasibility will also be assessed by other patient-related and block-related factors, as well as by factors related to the repositioning and plastering procedure.

NCT ID: NCT06107543 Recruiting - Lidocaine Clinical Trials

Lidocaine in the Prevention of Hemodynamic Response to Laryngoscopy and Endotracheal Intubation

Start date: December 1, 2023
Phase:
Study type: Observational

Direct laryngoscopy and endotracheal intubation procedure stimulate the sympathetic nervous system, causing catecholamine release into the circulation and consequently hemodynamic changes.There are many studies showing that lidocaine is used intravenously to suppress the sympathetic response to laryngoscopy and endotracheal intubation. Nebulized lidocaine is often used to provide upper airway local anesthesia in fiberoptic guided awake intubation. In this study, the researchers aimed to compare the results of using intravenous lidocaine and nebulized lidocaine to suppress the hemodynamic response caused by laryngoscopy and endotracheal intubation retrospectively. Researchers' hypothesis; Nebulized lidocaine administration is more effective than intravenous lidocaine administration in suppressing the hemodynamic response due to laryngoscopy and endotracheal intubation in patients under general anesthesia.

NCT ID: NCT06088875 Recruiting - Dexmedetomidine Clinical Trials

Nebulization Versus Spray-as-You-Go Airway Topical Anesthesia Using Dexmedetomidine and Lidocaine Mixture During Awake Flexible Fiberoptic Intubation in Temporomandibular Ankylosis

Start date: October 18, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to compare the efficacy of airway topical anesthesia with nebulization to the spray-as-you-go technique using dexmedetomidine and lidocaine mixture to achieve upper airway anesthesia in TMJ ankylosis patients.

NCT ID: NCT05937282 Recruiting - Dexmedetomidine Clinical Trials

Hemodynamic Responses of Dexmedetomidine, Lidocaine or Propofol Infusions During Laparoscopic Cholecystectomy

Start date: July 1, 2023
Phase: Phase 4
Study type: Interventional

This study will be carried out to compare the efficacy of dexmedetomidine, propofol or lidocaine infusions in attenuation of hemodynamic responses to pneumoperitoneum during adult laparoscopic cholecystectomy using electrical cardiometry.

NCT ID: NCT05717361 Recruiting - Pain, Postoperative Clinical Trials

Opioid Sparing Anesthesia in Cervical Spine Surgery

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

The aim of this double blind randomized study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of lidocaine and ketamine in the same syringe versus remifentanyl analgesia in cervical spine surgery.

NCT ID: NCT05594407 Recruiting - Pain, Postoperative Clinical Trials

Opioid Sparing Anesthesia in Lumbar Spine Surgery

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

The aim of this double blind randomized study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of dexmedetomidine-lidocaine-ketamine in the same syringe versus remifentanil analgesia in lumbar spine surgery

NCT ID: NCT05470166 Recruiting - Lidocaine Clinical Trials

Lidocaine Infusion With ERAS Protocol for Pancreatic Cancer Surgery: Effect on Pain and Patient Immunity.

ERAS
Start date: April 20, 2022
Phase: N/A
Study type: Interventional

The whole world now is directed to implement strategies that enhance the patient's quality of life and prevent tumor relapse. Enhanced recovery after pancreatic surgery (ERAPS) program was found to improve the quality of life as it is an evidence-based protocol designed to standardize and optimize perioperative medical care in order to reduce surgical trauma, perioperative physiological stress, organ dysfunction, reduction of clinical complications, length of hospital stay and the health costs together with increase of patient satisfaction. lidocaine; it is an amide local anaesthetic Recently its use as intravenous perioperative infusion for abdominal cancer surgeries is encouraging, as it significantly reduces postoperative pain, opioid consumption and nausea and vomiting. it also promotes gastrointestinal function recovery, and shortens the postoperative hospital stay. In addition, lidocaine in particular can act directly and indirectly on pancreatic cancer cells and the tumor microenvironment. The investigators suggest that IV lidocaine infusion in combination with ERAPS protocol may achieve better postoperative outcomes after pancreatic surgery for cancer.

NCT ID: NCT05243940 Recruiting - Analgesia Clinical Trials

Opioid-free Anesthesia in Thyroidectomies

Start date: March 7, 2022
Phase: N/A
Study type: Interventional

The aim of this study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of dexmedetomidine-lidocaine-ketamine in the same syringe versus fentanyl analgesia in elective thyroidectomies. Recovery parameters and nociception levels throughout the operation will be evaluated

NCT ID: NCT05158348 Recruiting - Dexmedetomidine Clinical Trials

A Comparative Study to Measure the Effect of Nebulized Dexmedetomidine

Start date: November 5, 2021
Phase: Phase 3
Study type: Interventional

A comparative study to measure the effect of nebulized dexmedetomidine - lidocaine for controlling postoperative pain after tonsillectomy in adults.

NCT ID: NCT05089526 Recruiting - Pain, Postoperative Clinical Trials

Opioid-free Anesthesia in Laparoscopic Cholecystectomies

Start date: October 11, 2021
Phase: N/A
Study type: Interventional

The aim of this study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of dexmedetomidine-lidocaine-ketamine in the same syringe versus fentanyl analgesia in elective laparoscopic cholecystectomies