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Laparoscopy clinical trials

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NCT ID: NCT03739944 Recruiting - Quality of Life Clinical Trials

Different Surgical Approaches in Patients of Early-stage Cervical Cancer

Start date: November 23, 2018
Phase: Phase 3
Study type: Interventional

This multi-center, randomized controlled study aims to compare the survival outcomes (including overall survival, progression-free survival and disease-free survival between Chinese uterine cervical patients receiving different surgical routes (laparotomy and laparoscopy) for radical hysterectomy or trachelectomy, which is the primary study objective. All patients with uterine cervical cancer of FIGO stage IA1 (with lymphovascular space invasion), IA2 and IB1 will be included and randomized into two groups: laparotomy and laparoscopy groups for radical hysterectomy or trachelectomy. Secondary study objectives include: patterns of recurrence, treatment-associated morbidity (6 months from surgery), cost-effectiveness, pelvic floor function, and quality of life.

NCT ID: NCT03738969 Recruiting - Recurrence Clinical Trials

Longitudinal Study of Different Surgical Approaches in Chinese Patients of Uterine Cervical Cancer

Start date: November 10, 2018
Phase:
Study type: Observational

This multi-center longitudinal study aims to compare the survival outcomes (including overall survival, progression-free survival and disease-free survival between uterine cervical patients receiving different surgical routes (vaginal, laparotomy and laparoscopy), which is the primary study objective. All clinical and pathological data would be retracted from case reviews, and all survival data would be reached by clinic, telephone and mail follow-up. This study also would analyze the impact on survival outcomes of other factors, including nerve-sparing techniques, neoadjuvant chemotherapy, neoadjuvant radiotherapy and infection of human papillomavirus. The predictive effects of different following protocol and imaging plans will be also compared. Last, the influences of surgical routes on the fertility outcomes (pregnancy and its complications) and the ovarian reserve are important secondary study objectives.

NCT ID: NCT03684291 Recruiting - Laparoscopy Clinical Trials

Hemodynamic Effects of Ventilation Modes

Start date: October 1, 2018
Phase:
Study type: Observational

Different ventilation modes can be used in laparoscopic surgeries. These surgeries are performed in steep Trendelenburg position with serious hemodynamic disturbances. This study aims to observe the hemodynamic effects of two different ventilation modes in laparoscopic gynecologic surgery performed in steep Trendelenburg position.

NCT ID: NCT03623399 Recruiting - Postoperative Pain Clinical Trials

Laparoscopic Gas Pressure and Postoperative Pain Score

Start date: August 7, 2018
Phase: N/A
Study type: Interventional

Aim of the study is to determine the effect of different laparoscopic intraoperative intraabdominal gas (CO2) pressures on the extent of postoperative pain scores.

NCT ID: NCT03427840 Recruiting - Pain, Postoperative Clinical Trials

Superior Hypogastric Plexus Blockade in Laparoscopic Hysterectomy

Start date: March 18, 2018
Phase:
Study type: Observational

The primary indication for superior hypogastric plexus (SHP) block is visceral pelvic pain, most commonly from malignancy of the ovary, uterus, cervix, bladder, rectum or prostate. Per-cutaneous SHP blocks should be done under guidance of ultrasonography, fluoroscopy, magnetic resonance or computed tomography. During minimally invasive laparoscopic surgery, percutaneous technique can be done under the guidance of cameras.

NCT ID: NCT02827292 Recruiting - Laparoscopy Clinical Trials

Effect of Music on Inflammatory Response During Laparoscopic Surgery

Start date: October 31, 2017
Phase: N/A
Study type: Interventional

This study evaluates the effect of per-operative music on the bio-molecular inflammatory response in laparoscopic surgery. Per-operative music intervention will be given to the test group via headphones while the control group will be applied headphones without any music (Silent). The inflammatory stress response will be measured postoperatively at 6 hours and 24 hours postoperatively along with the baseline levels measured preoperatively. The values will be compared between the test and control groups.

NCT ID: NCT01659489 Recruiting - Laparoscopy Clinical Trials

ADnexal TOrsion Markers Study

ATOMS
Start date: August 2012
Phase: N/A
Study type: Observational

Adnexal torsion , is a severe, though uncommon gynecological emergency, with a prevalence of 2.7-3%. The need for prompt diagnosis and treatment in order to save ovarian tissue has been realized a long time ago. A marker that will aid in the diagnosis of torsion and prevent missed diagnosis and unecessary loss of ovarian tissue, while not increasing the rate of unecessary laparoscopic interventions is much needed. To our knowledge, such marker has not been found. The purpose of this study is to find a marker using blood/serum from patients undergoing laparoscopy for suspected ovarian torsion

NCT ID: NCT01093430 Recruiting - Laparoscopy Clinical Trials

Is the Anterior Superior Iliac Spine a Useful Landmark at Laparoscopy?

Start date: September 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to study port symmetry and the incidence of anterior abdominal wall neuropathy associated with gynaecological surgery.

NCT ID: NCT01093079 Recruiting - Tumor Clinical Trials

Laparoscopic Versus Open Partial Nephrectomy - Surgical and Oncological Outcomes

LapVsOpen prtn
Start date: September 2009
Phase: N/A
Study type: Observational

Partial Nephrectomy is the standard care for small (<4 cm) renal tumors. Despite the expanding use of laparoscopic approach, debate exist regarding the short and long term outcomes compared to the open approach. Our goal is to perform a prospective randomized trial to compare these methods

NCT ID: NCT00625053 Recruiting - Quality of Life Clinical Trials

Functional Outcome After Incisional Hernia Repair: Open Versus Laparoscopic Repair

GINCISHERNIA
Start date: April 2008
Phase: Phase 4
Study type: Interventional

Background: Midline incisional hernia is reported from 0,5 to 11% after abdominal operations. Primary repair without mesh reinforcement is almost abandoned because of high recurrence rates (24 to 46%). Use of prosthetic mesh in incisional hernia repair lowered the recurrence rates under 10%. Recurrence rate alone is not the main quality criterion for incisional hernia repair anymore. Large series and meta-analyses confirmed the value of laparoscopic repair as at least equal if not better compared with open repair. Discomfort, pain, diminished quality of life and body image alteration influences functional well being. No baseline information exists in any of these fields treating pre- or post-operative phases in patients with incisional hernia. Respiratory functions and medico-economic evaluation are other rarely investigated fields that we consider in our trial. The objective of this study is to analyse the functional outcome status of patients after laparoscopic incisional hernia repair compared to open repair. Methods: A randomized controlled non-blinded clinical trial is designed to compare laparoscopic incisional hernia mesh repair with open repair on post operative pain, health related quality of life outcomes, body image and cosmetic measurements, respiratory functions, recurrence rates, and cost. Volunteers will be recruited in Geneva University Hospital, department of surgery, visceral surgery unit. Eligibility criteria is male patient aged over 18 years, with reducible incisional hernia who are candidates for elective surgery and medically fit for general anesthesia.30 patients will be enrolled for each group. Follow-up will take place at 10th, 30th days as well as 3 12 and 24 post operative months by questionnaires and by clinical exam by independent expert. An overall cost-analysis will be realized. Patient enrollment in the study will start in April 2008 and estimated to end in september 2009.