Obesity Clinical Trial
Official title:
The Relationship Between Monocyte-to-High-Density Lipoprotein Cholesterol Ratio, Metabolic Parameters and Excess Weight Loss in Patients Undergoing Laparoscopic Sleeve Gastrectomy
The present study hypothesized that significant weight loss is associated with a reduction in
the inflammatory markers, leading to diminished cardiovascular risks in patients undergoing
laparoscopic sleeve gastrectomy (LGS).
We found a decrease in MHR at postoperative 6 months from baseline in patients undergoing
LSG. The decrease in MHR was more remarkable with increasing percentage of EWL, but no
relationship between the %EWL and MHR.
The present study aims to evaluate the relationship between MHR, metabolic parameters and the
percentage of excess weight loss (%EWL) in participants undergoing laparoscopic sleeve
gastrectomy (LSG).
This prospective cohort study will evaluate obese participants undergoing LSG. Demographic
data of the participants and blood glucose level, monocyte count and lipid parameters
baseline and at 6 months after surgery will record. The MHR baseline and at 6 months after
surgery and the %EWL at 6 months after surgery will calculate. The participants will be
divide into two groups as participants with %EWL of <50 and patients with a %EWL of ≥50. The
parameters will compare between the two groups.
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