Combined Kinetic Chain Exercises on Knee Osteoarthritis

Knee Osteoarthritis Clinical Trial

Official title:

Combined Open And Closed Kinetic Chain Exercises On Static And Dynamic Strength Of Hamstring And Quadriceps In Knee Osteoarthritis Patients

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06233175
• Other study ID #: P.T.REC/012/004731
• Status: Recruiting
• Phase: N/A
• Start date: January 30, 2024
• Est. completion date: April 30, 2024

Study information

• Verified date: January 2024
• Source: Cairo University
• Contact: hadeer a el sayaad
• Phone: 01064125662
• Email: hadirelsayaad95[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

study will be conducted at faculty of physical therapy cairo university to investigate the effect of combined kinetic chain exercises on static and dynamic hamstring and quadriceps strength in knee osteoarthritis patients

Description:

the study will be conducted at faculty of physical therapy cairo university to investigate the effect of combined kinetic chain exercises on static and dynamic hamstring and quadriceps strength ,knee pain ,function ,H/Q ratio in knee osteoarthritis patients .using lafayette hand held dynamometer to measuring static strength of hamstring and quadriceps ,and free weight by Brzycki formula for measuring dynamic hamstring and quadriceps strength by determining 1 repetition maximum ,and pain measured by visual analogue scale (VAS) rating from (0 = no pain ) to (10= worst pain ) ,and function by Western Ontario and McMaster Universities Osteoarthritis Index questionnaire lower score indicate patient get better ,number of patients will be 34 divided into 2 groups ,each group will include 17 patient ,with 2 drop out according to sample size calculation ,each group will receive conventional tens for 20 min. and hot back for 15 min. and stretching exercises for hamstring,quadriceps,calf muscles ,while the experimental group will be increased by combined kinetic chain exercises

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 34
• Est. completion date: April 30, 2024
• Est. primary completion date: March 30, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 38 Years to 65 Years

Eligibility

Inclusion Criteria:

• the patients age from38 to 65
• recent radiographs confirming grade 2 and 3 (mild to moderate ) osteoarthritis
• primary and secondary Osteoarthritis
• both gender
• unilateral knee osteoarthritis
• pain in the knee for most days of prior month
• morning stiffness less than 30 min. in duration
• patient body mass index (BMI) between 18.5 and 29.9 kg/m2

Exclusion Criteria:

• neurological disorders
• wheelchair bound
• significant cognitive impairment
• present systemic inflammatory arthritis
• history of hip and knee arthroplasty
• history of trauma or surgical arthroscopy of either knee in the last 6 months
• received knee intra-articular injection within the last 3 months
• under anticoagulant therapy ,recent or imminent surgery (within 3 months)

Related Conditions & MeSH terms

• Knee Osteoarthritis
• Osteoarthritis
• Osteoarthritis, Knee

Intervention

Other:
• combined kinetic chain exercises
combined kinetic chain exercises in form of wall slide ,terminal knee extension ,forward step up and down ,side step up and down ,straight leg raise ,seated knee extension ,stretching exercises , hot back and trans cutaneous electrical stimulation,
• conventional
stretching exercises and hot back and trans cutaneous electrical stimulation,with out combined kinetic chain exercises

Locations

Country	Name	City	State
Egypt	Faculty of Physical Therapy	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	static quadriceps strength	measuring static quadriceps from sitting position at angle 60 and 90	Evaluation will be performed prior to the first treatment session ;as a baseline measure,and at last treatment session (after 4 weeks) as a post -treatment measure
Primary	static hamstring strength	measuring static hamstring strength from sitting position at angle 60 and 90	Evaluation will be performed prior to the first treatment session ;as a baseline measure,and at last treatment session (after 4 weeks) as a post -treatment measure
Primary	dynamic quadriceps strength	measuring dynamic quadriceps strength from sitting position by randomised free weight and Brzycki formula	Evaluation will be performed prior to the first treatment session ;as a baseline measure,and at last treatment session (after 4 weeks) as a post -treatment measure
Primary	dynamic hamstring strength	measuring dynamic hamstring strength from prone position by randomised free weight and Brzycki formula	Evaluation will be performed prior to the first treatment session ;as a baseline measure,and at last treatment session (after 4 weeks) as a post -treatment measure
Primary	Hamstring /Quadriceps ((H/Q) ratio	dividing static hamstring on static quadriceps strength and dynamic hamstring on dynamic quadriceps strength	Evaluation will be performed prior to the first treatment session ;as a baseline measure,and at last treatment session (after 4 weeks) as a post -treatment measure
Secondary	change in neck pain	by Visual Analog Scale (VAS) , (0=no pain ) and (10=worst pain)	Evaluation will be performed prior to the first treatment session ;as a baseline measure,and at last treatment session (after 4 weeks) as a post -treatment measure
Secondary	function	BYWestern Ontario and McMaster Universities Osteoarthritis Index questionnaire ,Lower score indicate patient gets better	Evaluation will be performed prior to the first treatment session ;as a baseline measure,and at last treatment session (after 4 weeks) as a post -treatment measure