The Level of Blood Brain Barrier Damage Biomarker in Acute Ischemic Stroke

Status Recruiting

Clinical Trial Summary

Hemorrhagic transformation is a common complication of acute ischemic stroke patients . BBB damage is regarded as a major pathophysiological mechanism of hemorrhagic transformation. So, the investigators hypothesis the level of BBB damage biomarker is predictor of intracranial hemorrhage following ischemic stroke.

Clinical Trial Description

Hemorrhagic transformation is a common complication of acute ischemic stroke patients . BBB injury often occurs in the early stage of ischemic stroke, leading brain tissue edema or even hemorrhagic transformation with the development of ischemic injury. The biomarker of BBB damage, such as the level of serum occludin, can reflect the extent of BBB injury. So, the investigators hypothesis the level of BBB damage biomarker is predictor of intracranial hemorrhage following ischemic stroke. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05321225
Study type	Observational [Patient Registry]
Source	Capital Medical University
Contact	xunming ji, MD PhD
Phone	86-10-83198952
Email	jixunming@vip.163.com
Status	Recruiting
Phase
Start date	March 10, 2022
Completion date	December 31, 2025

View Details

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