Ischemic Stroke Clinical Trial
Official title:
A Comparative Study of The Efficacy and Safety of Direct Mechanical Thrombectomy Versus Bridging Therapy in Large Vessel Occlusion: An Egyptian Single-Center Experience
Verified date | December 2021 |
Source | Alexandria University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This study compares the efficacy and safety of direct mechanical thrombectomy versus bridging therapy in patients with anterior circulation large vessel occlusion in a cohort of patients treated at the stroke unit of a single centre at Alexandria University in Egypt.
Status | Completed |
Enrollment | 51 |
Est. completion date | September 1, 2020 |
Est. primary completion date | July 1, 2020 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Patients with anterior ischemic stroke due to large vessel occlusion. - A previous autonomous modified Rankin Scale (mRS) of less than 2. - A National Institutes of Health Stroke Scale (NIHSS)=4 - A groin puncture within 4.5 hours of the neurological deficit onset. Exclusion Criteria: - Imaging documentation of intracranial haemorrhage - A premorbid mRS score of 2 or more - Absence of diffusion perfusion mismatch in CT perfusion. |
Country | Name | City | State |
---|---|---|---|
Egypt | Alexandria University Faculty of Medicine | Alexandria |
Lead Sponsor | Collaborator |
---|---|
Alexandria University |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Modified Rankin Scale score | A measurement of functional independence following ischemic stroke | 3 months | |
Primary | Complication rate | The rate and type of complications occuring postoperatively | within one week postoperatively | |
Secondary | The National Institutes of Health Stroke Scale (NIHSS) score | A validated scale for assessment of neurological dysfunction associated with stroke | at 24 hours postoperatively |
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