Ischemic Stroke Clinical Trial
Official title:
Affect of Multiple Health Education Interventions on Secondary Prevention Medication Persistence and Clinical Prognosis of Ischemic Stroke Patients: a Prospective Cohort Study
The study aimed to demonstrate the relationship between secondary prevention medication persistence and clinical prognosis of ischemic stroke patients at 3,6,12 months
The study is a prospective, multicenter, hospital-based study on secondary prevention for
patients with ischemic cerebrovascular diseases between May 2014 and June 2015. Physicians
from 24 hospitals in Beijing underwent a standard secondary prevention training of ischemic
cerebrovascular diseases by professional training, instruction manuals, stratification
management software. In order to improve the persistence of taking preventive secondary
medicine, IS patients from these 24 hospitals received healthy education through manuals and
Digital Video Disc about health education during hospitalization and acquired secondary
preventive knowledge of ischemic cerebrovascular diseases through regular health education
messages during 6 months after discharge. Patients with IS from other 6 hospitals were used
as a control, and no such intervention was given to them.
Telephone follow-up was performed at 3 months, 6 months, and 1 year after the onset of
cerebral infarction, during which the use of antiplatelet and statins drugs and recurrence of
IS were recorded. Patients who took antiplatelet drugs or statins at three follow-ups were
regarded as persistent antiplatelet drugs or statins taking within one year after the onset
of the disease. The main prognostic indicator was the recurrence of IS and persistence of
antiplatelet and statins medication within 1 year, and the main purpose was to explore the
impact of persistent statins and antiplatelet medication use on IS recurrence.
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