Presence of Minor Anti Phospholipid Antibodies in Blood Samples of Ischemic Stroke Patients and Healthy Controls

Ischemic Stroke Clinical Trial

Official title:

Presence of Minor Anti Phospholipid Antibodies in Blood Samples of Ischemic Stroke Patients and Healthy Controls.

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT01487746
• Other study ID #: 0125-11-MMC
• Status: Not yet recruiting
• Phase: N/A
• First received: December 5, 2011
• Last updated: December 6, 2011
• Start date: December 2011
• Est. completion date: September 2012

Study information

• Verified date: December 2011
• Source: Meir Medical Center
• Contact: Yair Levy, Prof.
• Phone: 0533671735
• Email: levy.yair[@]clalit.org.il,
• Is FDA regulated: No
• Health authority: Israel: Clalit Health Services
• Study type: Observational

Clinical Trial Summary

The investigators expect to find higher levels of both classical and minor antiphospholipid (APL) antibodies among the stroke cases. Furthermore, the investigators expect to find not only classical APLA but also minor antibodies.

The investigators believe that minor antibodies have a major role in the hypercoagulability state.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 207
• Est. completion date: September 2012
• Est. primary completion date: March 2012
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• stroke diagnosis

• blood sampling within 36hrs from the event

• written agreement

Exclusion Criteria:

• a stroke, MI or major operation prior to the current stroke

• hypercoagulable state known in this patient

• a severe chronic disease known at the time of the stroke

• an infection on arrival (based on anamnesis, physical exam and lab tests)

• thrombolytic treatment

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

• Ischemia
• Ischemic Stroke
• Stroke

Locations

Country	Name	City	State
Israel	Meir health center	Kfar-saba

Sponsors (2)

Lead Sponsor	Collaborator
Meir Medical Center	Sheba Medical Center

Country where clinical trial is conducted

Israel,