Ischemic Stroke Clinical Trial
Official title:
Predictors Of Stroke Outcome In Children Admitted To Assiut University Children Hospital
Verified date | September 2019 |
Source | Assiut University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Stroke can be defined as an abrupt loss of brain function that is caused by decreased
cerebral blood flow.
Stroke can occur at all stages of life, but presentation is variable depending on age,
involved artery, and underlying risk factors.
Status | Not yet recruiting |
Enrollment | 30 |
Est. completion date | December 1, 2021 |
Est. primary completion date | December 1, 2020 |
Accepts healthy volunteers | |
Gender | All |
Age group | 1 Month to 18 Years |
Eligibility |
Inclusion Criteria: - - Infant and Children around age of (1month to 18years old) of both sexes were diagnosed as stroke (hemorrhagic or ischemic) by CT or MRI. Exclusion Criteria: - - Neonates (less than one month) - Stroke caused by trauma - Patient refusal to participate the research |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Assiut University |
Chiang KL, Cheng CY. Epidemiology, risk factors and characteristics of pediatric stroke: a nationwide population-based study. QJM. 2018 Jul 1;111(7):445-454. doi: 10.1093/qjmed/hcy066. — View Citation
Goeggel Simonetti B, Cavelti A, Arnold M, Bigi S, Regényi M, Mattle HP, Gralla J, Fluss J, Weber P, Hackenberg A, Steinlin M, Fischer U. Long-term outcome after arterial ischemic stroke in children and young adults. Neurology. 2015 May 12;84(19):1941-7. doi: 10.1212/WNL.0000000000001555. Epub 2015 Apr 10. — View Citation
McKinney SM, Magruder JT, Abramo TJ. An Update on Pediatric Stroke Protocol. Pediatr Emerg Care. 2018 Nov;34(11):810-815. doi: 10.1097/PEC.0000000000001653. Review. — View Citation
Studer M, Boltshauser E, Capone Mori A, Datta A, Fluss J, Mercati D, Hackenberg A, Keller E, Maier O, Marcoz JP, Ramelli GP, Poloni C, Schmid R, Schmitt-Mechelke T, Wehrli E, Heinks T, Steinlin M. Factors affecting cognitive outcome in early pediatric stroke. Neurology. 2014 Mar 4;82(9):784-92. doi: 10.1212/WNL.0000000000000162. Epub 2014 Jan 31. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Computed tomography(CT) of the brain | To detect the stroke type ;(hemorrhagic or ischemic) , location and severity at admission (at start of the study) and after discharge (6 months after discharge) . | Baseline to 6 months after discharge | |
Primary | Brain magnetic resonance imaging (MRI) | It is more sensitive than brain CT in diagnosis and detection of pediatric stroke including AIS , vascular malformations , and central nervous system inflammatory changes. | 1Year | |
Primary | Glasgow coma scale(GCS). | To assess the level of consciousness to evaluate the extent of brain damage;(15_12) mild brain damage,(12_8) moderate brain damage,(<8 )severe brain damage. | 1 year |
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