CWT Versus AT on Selected Cardiovascular Indices and Functional Capacity in Patients With Ischemic Cardiomyopathy.

Ischemic Cardiomyopathy Clinical Trial

Official title:

Circuit Weight Versus Aerobic Training on Selected Cardiovascular Indices and Functional Capacity in Patients With Ischemic Cardiomyopathy.

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05674955
• Other study ID #: Cw versus AT in cardiomyopathy
• Status: Not yet recruiting
• Phase: N/A
• Start date: February 8, 2024
• Est. completion date: March 8, 2024

Study information

• Verified date: February 2024
• Source: Cairo University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

To compare between the effect of circuit weight and aerobic training on selected cardiovascular indices and functional capacity in patients with ischemic cardiomyopathy.

Description:

Ischemic cardiomyopathy (ICM) is a term that refers to the heart's decreased ability to pump blood properly due to myocardial damage brought upon by ischemia. Ischemic cardiomyopathy has a spectrum of clinical changes which eventually leads to congestive heart failure (CHF). Initially, there is a reversible loss of cardiac contractile function because of decreased oxygen supply to the heart muscle; however, when there is ischemia for a prolonged period, there is irreversible cardiac muscle damage resulting in cardiac remodeling. Remodeling is primarily achieved by myocardial fibrosis which results in decreased cardiac function, arrhythmia, and possible cardiac conduction system impairment. In ischemic cardiomyopathy, there is a significant impairment of the left ventricular systolic function, with a left ventricular ejection fraction (LVEF) less than 40% (Bhandari et al., 2021).

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 60
• Est. completion date: March 8, 2024
• Est. primary completion date: March 5, 2024
• Accepts healthy volunteers: No
• Gender: Male
• Age group: 45 Years to 55 Years

Eligibility

Inclusion Criteria:

• Sixty male patients with ischemic cardiomyopathy as a result of a recent acute myocardial infarction event (=2 months) with 40%<LVEF<50%.
• They are functionally classified as class II according to New York Heart Association (NYHA).
• Their age will be ranged from 45 to 55 years old.
• Their BMI will be ranged from 25 to 29.9 kg/m².
• They will have good mentality.

Exclusion Criteria:

• Recurrent coronary heart disease.
• Severe valvular diseases.
• Underlying pulmonary disease (aspiration pneumonia, chronic obstructive pulmonary disease, pneumothorax, etc.).
• Inability to ambulate owing to physical problems (paresis induced by cerebral stroke, spinal cord injury, amputation, severe pain, dyspnea, etc.).
• muskloskletal problems (e.g. severe osteoarthritis or ankylosing spondylitis).
• Impaired cognitive function (vascular dementia, Alzheimer's dementia, other psychological disease, etc.)

Related Conditions & MeSH terms

• Cardiomyopathies
• Ischemia
• Ischemic Cardiomyopathy

Intervention

Diagnostic Test:
• Circuit weight versus aerobic training
Circuit weight :Duration: 30 min-60 min (total session) Frequency: 3 times / week. Intensity: increased load was established when subject was able to complete 12 repetitions ( Wayne, 2014) B- Aerobic training: This mode of exercise will be conducted for study group B as follows: Intensity: started by 60-85% of target heart rate according to each patient response Target heart rate (THR) = 60% -85% (maximum heart rate-resting heart rate) + resting heart rate Maximum heart rate (MHR) = (220-Age). Mode: Walking on treadmill. Duration: Each session consisted of 10 minutes warming up firstly then 30 minutes time of session ended by 10 minutes cool down exercises. Frequency: Three times / week (Nishi et al., 2011). C-Traditional medical treatment: This treatment will be conducted for all group A, B and C.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

References & Publications (1)

Nishi I, Noguchi T, Iwanaga Y, Furuichi S, Aihara N, Takaki H, Goto Y. Effects of exercise training in patients with chronic heart failure and advanced left ventricular systolic dysfunction receiving beta-blockers. Circ J. 2011;75(7):1649-55. doi: 10.1253 — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Ejection fraction	Will be measured by precentge	2 months
Secondary	Blood pressure	Will be measured by mmhg	2 months