Ischaemic Stroke Clinical Trial
Official title:
Diagnosis and Treatment of Minor Ischaemic Stroke According to the Etiology and Pathogenesis
Negligence or contempt of the etiology and pathogenesis of minor ischaemic stroke in the
early diagnosis and effective treatment leads to more than 40-50% of patient with recurrent
episodes, and 10% patient died. Therefore, diagnosis and treatment of minor ischaemic stroke
according to the etiology and pathogenesis is important.
The 2007 Korean modified TOAST type got some progress, but there exists two major
disadvantages: imperfect diagnosis and pathogenesis of perforator artery infarction
etiology; lack of typing according to the pathogenesis of large atherosclerotic infarction
and taking measures of treatment according to the new types. Recently, domestic professor
Gaoshan proposes new approach to diagnose and treat minor ischaemic stroke according to the
etiology and pathogenesis of CISS typing, but the pathogenesis of hypoperfusion infarction
with severe stenosis of large artery is unclear. Is it low perfusion? Or artery-artery
embolization? Or both? How to distinguish the pathogenesis of branch artery disease: by
atherosclerosis? Or hyalinosis? Or both? How to check the validity of clinical types? This
study take different interventions according to different types and observation of the long
term clinical results of intervention( mortality, recurrence rate, disability rate and rate
of cerebral hemorrhage and subarachnoid hemorrhage), in order to clarify the new types can
indeed solve the current problem of minor ischaemic stroke with high mortality, recurrence
rate, disability rate and rate of cerebral hemorrhage and subarachnoid hemorrhage.
n/a
Observational Model: Case-Only, Time Perspective: Prospective
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03148457 -
Early Versus Late Initiation of Direct Oral Anticoagulants in Post-ischaemic Stroke Patients With Atrial fibrillatioN (ELAN): an International, Multicentre, Randomised-controlled, Two-arm, Assessor-blinded Trial
|
N/A | |
| Recruiting |
NCT05922540 -
a Cohort Study of Ischemic Cerebrovascular Disease
|
||
| Completed |
NCT02122718 -
XILO-FIST, the Effect of Allopurinol on the Brain Heart and Blood Pressure After Stroke
|
Phase 4 | |
| Completed |
NCT04260347 -
SITS-IVT in Patients >80 Years Study
|
||
| Completed |
NCT02205424 -
Cognition And Neocortical Volume After Stroke
|
||
| Completed |
NCT02117635 -
Pilot Investigation of Stem Cells in Stroke Phase II Efficacy
|
Phase 2 | |
| Completed |
NCT02155907 -
Atrial Fibrillation Detected by ELR and Holter Recording, a Comparison in Patients With Ischemic Stroke or TIA
|
||
| Completed |
NCT02073773 -
Combinational Rehabilitative Therapy and Functional Brain Imaging for Patients Recovering From Motor Stroke
|
Phase 3 | |
| Active, not recruiting |
NCT01864031 -
The Role of Alcohol Consumption in the Aetiology of Different Cardiovascular Disease Phenotypes: a CALIBER Study
|
N/A | |
| Active, not recruiting |
NCT02360670 -
Penumbra and Recanalisation Acute Computed Tomography in Ischaemic Stroke Evaluation
|
N/A | |
| Completed |
NCT02928926 -
Cerebral Haemodynamics in Stroke Thrombolysis Study (CHIST)
|